PDB entry 1kpr

View 1kpr on RCSB PDB site
Description: The human non-classical major histocompatibility complex molecule HLA-E
Class: immune system
Keywords: HLA-E, MHC, non-classical MHC, HLA, BETA 2 MICROGLOBULIN, IMMUNE SYSTEM
Deposited on 2002-01-02, released 2003-02-25
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.235
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-E
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13747 (0-273)
      • engineered (106)
      • engineered (255)
    Domains in SCOPe 2.02: d1kpra1, d1kpra2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (0-99)
      • cloning artifact (0)
    Domains in SCOPe 2.02: d1kprb_
  • Chain 'C':
    Compound: hla class I histocompatibility antigen, alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-E
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13747 (0-273)
      • engineered (106)
      • engineered (255)
    Domains in SCOPe 2.02: d1kprc1, d1kprc2
  • Chain 'D':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (0-99)
      • cloning artifact (0)
    Domains in SCOPe 2.02: d1kprd_
  • Chain 'P':
    Compound: Peptide VMAPRTVLL
    Database cross-references and differences (RAF-indexed):
    • PDB 1KPR (0-8)
  • Chain 'Q':
    Compound: Peptide VMAPRTVLL
    Database cross-references and differences (RAF-indexed):
    • PDB 1KPR (0-8)
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kprA (A:)
gshslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseyw
dretrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdgrflrgyeqfaydg
kdyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketll
hleppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgt
fqkwaavvvpsgeeqaytchvqheglpepvtlrw

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kprB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kprC (C:)
gshslkyfhtsvsrpgrgeprfisvgyvddtqfvrfdndaasprmvprapwmeqegseyw
dretrsardtaqifrvnlrtlrgyynqseagshtlqwmhgcelgpdgrflrgyeqfaydg
kdyltlnedlrswtavdtaaqiseqksndaseaehqrayledtcvewlhkylekgketll
hleppkthvthhpisdheatlrcwalgfypaeitltwqqdgeghtqdtelvetrpagdgt
fqkwaavvvpsgeeqaytchvqheglpepvtlrw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kprD (D:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.