PDB entry 1klj

View 1klj on RCSB PDB site
Description: Crystal structure of uninhibited factor VIIa
Class: hydrolase
Keywords: extrinsic coagulation pathway, serine protease activation, rational drug design, substrate-assisted catalysis, HYDROLASE
Deposited on 2001-12-12, released 2002-10-09
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: 0.231
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: factor VIIa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1kljh_
  • Chain 'L':
    Compound: factor VIIa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1kljl_
  • Heterogens: CA, EDO, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1kljH (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
    sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
    seprpgvllrapfp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kljH (H:)
    ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
    lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
    lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrniteymfcagysdgskd
    sckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprpg
    vllrapfp
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1kljL (L:)
    hkddqlicvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilek
    rnaskpqgr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1kljL (L:)
    licvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr