PDB entry 1klg

View 1klg on RCSB PDB site
Description: Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Class: immune system/toxin
Keywords: HLA-DR1/TPI, enterotoxin C3, human melanoma antigen, CD4+ T cells, IMMUNE SYSTEM/TOXIN COMPLEX
Deposited on 2001-12-11, released 2002-08-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-19.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.206
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1klga1, d1klga2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen, dr-1 beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1klgb1, d1klgb2
  • Chain 'C':
    Compound: Triosephosphate isomerase peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1KLG (0-14)
  • Chain 'D':
    Compound: Enterotoxin type C-3
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0L5 (0-238)
      • engineered (42)
      • engineered (44-46)
    Domains in SCOPe 2.05: d1klgd1, d1klgd2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1klgA (A:)
    ehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalani
    avdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwlr
    ngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1klgB (B:)
    gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqplqhhnllvcsvs
    gfypgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1klgB (B:)
    gdtrprflwqlkfechffngtervrllerciynqeesvrfdsdvgeyravtelgrpdaey
    wnsqkdlleqrraavdtycrhnygvgesftvqrrvepkvtvypsktqhhnllvcsvsgfy
    pgsievrwfrngqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsvtsp
    ltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1klgD (D:)
    esqpdpmpddlhksseftgtmgnmkylyddhyvsatkvksvdsffkwdliynisdkklkn
    ydkvktellnedlakkykdevvdvygsnyyvncyfsskdnvgkvtggktcmyggitkheg
    nhfdngnlqnvlvrvyenkrntisfevqtdkksvtaqeldikarnflinkknlyefnssp
    yetgyikfienngntfwydmmpapgdkfdqskylmmyndnktvdsksvkievhlttkng
    

    Sequence, based on observed residues (ATOM records): (download)
    >1klgD (D:)
    esqpdpmpddlhksseftgtmgnmkylyddhyvsatkvksvdsffkwdliynisdkklkn
    ydkvktellnedlakkykdevvdvygsnyyvncyfsskgktcmyggitkhegnhfdngnl
    qnvlvrvyenkrntisfevqtdkksvtaqeldikarnflinkknlyefnsspyetgyikf
    ienngntfwydmmpapgdkfdqskylmmyndnktvdsksvkievhlttkng