PDB entry 1kim

View 1kim on RCSB PDB site
Description: crystal structure of thymidine kinase from herpes simplex virus type I complexed with deoxythymidine
Class: transferase
Keywords: transferase, phosphotransferase, thymidine kinase, viridae, ds-DNA enveloped viruses, herpesviridae, alphaherpesvirinae
Deposited on 1997-11-12, released 1998-05-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: 0.209
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • PIR KIBET
    Domains in SCOPe 2.07: d1kima_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK
    Database cross-references and differences (RAF-indexed):
    • PIR KIBET
    Domains in SCOPe 2.07: d1kimb_
  • Heterogens: SO4, THM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kimA (A:)
safdqaarsrghsnrrtalrprrqqeatevrpeqkmptllrvyidgphgmgkttttqllv
algsrddivyvpepmtywrvlgasetianiyttqhrldqgeisagdaavvmtsaqitmgm
pyavtdavlaphiggeagsshapppaltlifdrhpiaallcypaarylmgsmtpqavlaf
valipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaairrvygllantvrylq
cggswredwgqlsgtavppqgaepqsnagprphigdtlftlfrapellapngdlynvfaw
aldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfar
emgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1kimA (A:)
mptllrvyidgphgmgkttttqllvdivyvpepmtywrvlgasetianiyttqhrldqge
isagdaavvmtsaqitmgmpyavtdavlaphiggeagppaltlifdrhpiaallcypaar
ylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaair
rvygllantvrylqcggswredwgqlsgprphigdtlftlfrapellapngdlynvfawa
ldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfare
mgea

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1kimB (B:)
safdqaarsrghsnrrtalrprrqqeatevrpeqkmptllrvyidgphgmgkttttqllv
algsrddivyvpepmtywrvlgasetianiyttqhrldqgeisagdaavvmtsaqitmgm
pyavtdavlaphiggeagsshapppaltlifdrhpiaallcypaarylmgsmtpqavlaf
valipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaairrvygllantvrylq
cggswredwgqlsgtavppqgaepqsnagprphigdtlftlfrapellapngdlynvfaw
aldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfar
emgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1kimB (B:)
mptllrvyidgphgmgkttttqllvalgdivyvpepmtywrvlgasetianiyttqhrld
qgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagppaltlifdrhpiaallcyp
aarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamla
airrvygllantvrylqcggswredwgqlsagprphigdtlftlfrapellapngdlynv
fawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlart
faremgea