PDB entry 1ki4

View 1ki4 on RCSB PDB site
Description: crystal structure of thymidine kinase from herpes simplex virus type I complexed with 5-bromothienyldeoxyuridine
Class: phosphotransferase
Keywords: phosphotransferase, thymidine kinase, viridae, ds-DNA enveloped viruses, herpesviridae, alphaherpesvirinae, substrate analog, 5-bromothienyldeoxyuridine
Deposited on 1998-05-18, released 1998-12-02
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: 0.21
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1ki4a_
  • Chain 'B':
    Compound: Thymidine kinase
    Species: HERPES SIMPLEX VIRUS (TYPE 1 / STRAIN 17) [TaxId:10299]
    Gene: TK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d1ki4b_
  • Heterogens: SO4, BTD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ki4A (A:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1ki4A (A:)
mptllrvyidgphgmgkttttqllvdivyvpepmtywrvlgasetianiyttqhrldqge
isagdaavvmtsaqitmgmpyavtdavlaphiggeagppaltlifdrhpiaallcypaar
ylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamlaair
rvygllantvrylqcggswredwgqlsgprphigdtlftlfrapellapngdlynvfawa
ldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartfare
mge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ki4B (B:)
mptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttqh
rldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrhp
iaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpge
rldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphig
dtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlts
gmvqthvttpgsipticdlartfaremgean

    Sequence, based on observed residues (ATOM records): (download) 
    >1ki4B (B:)
mptllrvyidgphgmgkttttqllvalgdivyvpepmtywrvlgasetianiyttqhrld
qgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagppaltlifdrhpiaallcyp
aarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamla
airrvygllantvrylqcggswredwgqlsagprphigdtlftlfrapellapngdlynv
fawaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlart
faremge