PDB entry 1khx

View 1khx on RCSB PDB site
Description: Crystal structure of a phosphorylated Smad2
Class: transcription
Keywords: TGF-beta signaling, Smad2, phosphorylation, receptor kinase signaling, cancer, TRANSCRIPTION
Deposited on 2001-12-01, released 2002-02-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.215
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Smad2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15796 (Start-226)
      • modified residue (224)
      • modified residue (226)
    Domains in SCOPe 2.06: d1khxa_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1khxA (A:)
mdtgspaelspttlspvnhsldlqpvtysepafwcsiayyelnqrvgetfhasqpsltvd
gftdpsnserfclgllsnvnrnatvemtrrhigrgvrlyyiggevfaeclsdsaifvqsp
ncnqrygwhpatvckippgcnlkifnnqefaallaqsvnqgfeavyqltrmctirmsfvk
gwgaeyrrqtvtstpcwielhlngplqwldkvltqmgspsvrcssms

    Sequence, based on observed residues (ATOM records): (download) 
    >1khxA (A:)
pvtysepafwcsiayyelnqrvgetfhasqpsltvdgftdpsnserfclgllsnvnrnat
vemtrrhigrgvrlyyiggevfaeclsdsaifvqspncnqrygwhpatvckippgcnlki
fnnqefaallaqsvnqgfeavyqltrmctirmsfvkgwgaeyrrqtvtstpcwielhlng
plqwldkvltqmgspsvrcssms