PDB entry 1khe

View 1khe on RCSB PDB site
Description: PEPCK complex with nonhydrolyzable GTP analog, MAD data
Class: lyase
Keywords: Gluconeogenesis, P-loop
Deposited on 2001-11-29, released 2002-02-27
The last revision prior to the SCOP 1.75 freeze date was dated 2002-02-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.174
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphoenolpyruvate carboxykinase, cytosolic (GTP)
    Species: HOMO SAPIENS
    Gene: PCK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35558 (Start-624)
      • modified residue (62)
      • modified residue (119)
      • modified residue (136)
      • modified residue (141)
      • modified residue (148)
      • modified residue (172)
      • modified residue (175)
      • modified residue (178)
      • modified residue (252)
      • modified residue (267)
      • variant (269)
      • modified residue (297-298)
      • modified residue (317)
      • modified residue (462)
      • modified residue (478)
      • modified residue (484)
      • modified residue (502)
      • modified residue (542)
      • modified residue (576-577)
      • variant (588)
      • variant (599)
      • modified residue (624)
    Domains in SCOP 1.75: d1khea1, d1khea2
  • Heterogens: MN, GCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1kheA (A:)
gelmppqlqnglnlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrll
gqmeeegilrrlkkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwm
seedfekafnarfpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmg
tpvlealgdgefvkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgygg
nsllgkkcfalrmasrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammn
pslpgwkvecvgddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntif
tnvaetsdggvywegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiid
aawespegvpiegiifggrrpagvplvyealswqhgvfvgaamrseataaaehkgkiimh
dpfamrpffgynfgkylahwlsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvl
ewmfnridgkastkltpigyipkedalnlkglghinmmelfsiskefwdkevediekylv
dqvnadlpceiereilalkqrisqm

    Sequence, based on observed residues (ATOM records): (download) 
    >1kheA (A:)
nlsakvvqgsldslpqavreflennaelcqpdhihicdgseeengrllgqmeeegilrrl
kkydncwlaltdprdvariesktvivtqeqrdtvpipktglsqlgrwmseedfekafnar
fpgcmkgrtmyvipfsmgplgsplskigieltdspyvvasmrimtrmgtpvlealgdgef
vkclhsvgcplplqkplvnnwpcnpeltliahlpdrreiisfgsgyggnsllgkkcfalr
masrlakeegwlaehmlvlgitnpegekkylaaafpsacgktnlammnpslpgwkvecvg
ddiawmkfdaqghlrainpengffgvapgtsvktnpnaiktiqkntiftnvaetsdggvy
wegideplasgvtitswknkewssedgepcahpnsrfctpasqcpiidaawespegvpie
giifggrrpagvplvyealswqhgvfvgaamrseakiimhdpfamrpffgynfgkylahw
lsmaqhpaaklpkifhvnwfrkdkegkflwpgfgensrvlewmfnridgstkltpigyip
kedalnlkglghinmmelfsiskefwdkevediekylvdqvnadlpceiereilalkqri
sqm