PDB entry 1kfx

View 1kfx on RCSB PDB site
Description: Crystal Structure of Human m-Calpain Form I
Class: hydrolase
Keywords: regulation, papain-like, thiol-protease, hydrolase
Deposited on 2001-11-23, released 2001-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-05-02, with a file datestamp of 2012-04-27.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.243
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'L':
    Compound: m-calpain large subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1kfxl1, d1kfxl2, d1kfxl3
  • Chain 'S':
    Compound: m-calpain small subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1kfxs_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1kfxL (L:)
agiaaklakdreaaeglgsheraikylnqdyealrnecleagtlfqdpsfpaipsalgfk
elgpyssktrgmrwkrpteicadpqfiiggatrtdicqgalgdcwllaaiasltlneeil
arvvplnqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelkkpppnlfkiiqkalqkgsllgcs
iditsaadseaitfqklvkghaysvtgaeevesngslqklirirnpwgevewtgrwndnc
pswntidpeererltrrhedgefwmsfsdflrhysrleicnltpdtltsdtykkwkltkm
dgnwrrgstaggcrnypntfwmnpqylikleeededeedgesgctflvgliqkhrrrqrk
mgedmhtigfgiyevpeelsgqtnihlsknffltnrarersdtfinlrevlnrfklppge
yilvpstfepnkdgdfcirvfsekkadyqavddeieanleefdiseddiddgvrrlfaql
agedaeisafelqtilrrvlakrqdiksdgfsietckimvdmldsdgsgklglkefyilw
tkiqkyqkiyreidvdrsgtmnsyemrkaleeagfkmpcqlhqvivarfaddqliidfdn
fvrclvrletlfkifkqldpentgtieldliswlcfsvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1kfxL (L:)
agiaaklakdreaaeglgsheraikylnqdyealrnecleagtlfqdpsfpaipsalgfk
elgpyssktrgmrwkrpteicadpqfiiggatrtdicqgalgdcwllaaiasltlneeil
arvvplnqsfqenyagifhfqfwqygewvevvvddrlptkdgellfvhsaegsefwsall
ekayakingcyealsggattegfedftggiaewyelkkpppnlfkiiqkalqkgsllgcs
idkghaysvtgaeevesngslqklirirnpwgevewtgrwmsfsdflrhysrleicnltp
dtltsdtykkwkltkmdgnwrrgstaggcrnypntfwmnpqylikleeedectflvgliq
khrrrqrkmgedmhtigfgiyevpeetnihlsknffltnrarersdtfinlrevlnrfkl
ppgeyilvpstfepnkdgdfcirvfsekkadyqavddeieanleefdiseddiddgvrrl
faqlagedaeisafelqtilrrvlakrksdgfsietckimvdmldsdgsgklglkefyil
wtkiqkyqkiyreidvdrsgtmnsyemrkaleeagfkmpcqlhqvivarfaddqliidfd
nfvrclvrletlfkifkqldpentgtieldliswlcfsvl

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >1kfxS (S:)
thysnieaneseevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtc
rsmvavmdsdttgklgfeefkylwnnikrwqaiykqfdtdrsgticsselpgafeaagfh
lnehlynmiirrysdesgnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlql
tmys

    Sequence, based on observed residues (ATOM records): (download) 
    >1kfxS (S:)
neseevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmd
sdttgklgfeefkylwnnikrwqaiykqfdtdrsgticsselpgafeaagfhlnehlynm
iirrysdesgnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlqltmys