PDB entry 1kae

View 1kae on RCSB PDB site
Description: l-histidinol dehydrogenase (hisd) structure complexed with l-histidinol (substrate), zinc and nad (cofactor)
Class: oxidoreductase
Keywords: l-histidinol dehydrogenase, homodimer, rossmann fold, 4 domains, hisd, l-histidine biosynthesis, nad cofactor, oxidoreductase
Deposited on 2001-11-01, released 2002-06-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.213
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histidinol dehydrogenase
    Species: Escherichia coli [TaxId:562]
    Gene: hisD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06988 (0-433)
      • modified residue (0)
      • see remark 999 (14)
      • modified residue (21)
      • modified residue (87)
      • modified residue (143)
      • see remark 999 (149)
      • modified residue (231)
      • modified residue (276)
      • see remark 999 (312)
      • modified residue (389)
      • see remark 999 (402)
    Domains in SCOPe 2.05: d1kaea_
  • Chain 'B':
    Compound: Histidinol dehydrogenase
    Species: Escherichia coli [TaxId:562]
    Gene: hisD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06988 (0-433)
      • modified residue (0)
      • see remark 999 (14)
      • modified residue (21)
      • modified residue (87)
      • modified residue (143)
      • see remark 999 (149)
      • modified residue (231)
      • modified residue (276)
      • see remark 999 (312)
      • modified residue (389)
      • see remark 999 (402)
    Domains in SCOPe 2.05: d1kaeb_
  • Heterogens: SO4, ZN, DTT, IMD, HSO, NAD, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kaeA (A:)
msfntiidwnsctaeqqrqllmrpaisasesitrtvndildnvkargdealreysakfdk
ttvtalkvsaeeiaaaserlsdelkqamavavknietfhtaqklppvdvetqpgvrcqqv
trpvasvglyipggsaplfstvlmlatpasiagckkvvlcspppiadeilyaaqlcgvqd
vfnvggaqaiaalafgtesvpkvdkifgpgnafvteakrqvsqrldgaaidmpagpsevl
viadsgatpdfvasdllsqaehgpdsqvilltpaadmarrvaeaverqlaelpraetarq
alnasrlivtkdlaqcveisnqygpehliiqtrnarelvdsitsagsvflgdwspesagd
yasgtnhvlptygytatcsslgladfqkrmtvqelskegfsalastietlaaaerltahk
navtlrvnalkeqa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1kaeB (B:)
msfntiidwnsctaeqqrqllmrpaisasesitrtvndildnvkargdealreysakfdk
ttvtalkvsaeeiaaaserlsdelkqamavavknietfhtaqklppvdvetqpgvrcqqv
trpvasvglyipggsaplfstvlmlatpasiagckkvvlcspppiadeilyaaqlcgvqd
vfnvggaqaiaalafgtesvpkvdkifgpgnafvteakrqvsqrldgaaidmpagpsevl
viadsgatpdfvasdllsqaehgpdsqvilltpaadmarrvaeaverqlaelpraetarq
alnasrlivtkdlaqcveisnqygpehliiqtrnarelvdsitsagsvflgdwspesagd
yasgtnhvlptygytatcsslgladfqkrmtvqelskegfsalastietlaaaerltahk
navtlrvnalkeqa