PDB entry 1k4t

View 1k4t on RCSB PDB site
Description: human dna topoisomerase i (70 kda) in complex with the poison topotecan and covalent complex with a 22 base pair dna duplex
Deposited on 2001-10-08, released 2002-12-04
The last revision prior to the SCOP 1.67 freeze date was dated 2002-12-04, with a file datestamp of 2002-12-04.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.229
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1k4tA (A:)
kkpknkdkdkkvpepdnkkkkpkkeeeqkwkwweeerypegikwkflehkgpvfappyep
lpenvkfyydgkvmklspkaeevatffakmldheyttkeifrknffkdwrkemtneekni
itnlskcdftqmsqyfkaqtearkqmskeeklkikeenekllkeygfcimdnhkerianf
kieppglfrgrgnhpkmgmlkrrimpediiincskdakvpspppghkwkevrhdnkvtwl
vswteniqgsikyimlnpssrikgekdwqkyetarrlkkcvdkirnqyredwkskemkvr
qravalyfidklalragnekeegetadtvgccslrvehinlhpeldgqeyvvefdflgkd
siryynkvpvekrvfknlqlfmenkqpeddlfdrlntgilnkhlqdlmegltakvfrtyn
asitlqqqlkeltapdenipakilsynranravailcnhqrappktfeksmmnlqtkida
kkeqladarrdlksakadakvmkdaktkkvveskkkavqrleeqlmklevqatdreenkq
ialgtsklnyldpritvawckkwgvpiekiynktqrekfawaidmadedyef

    Sequence, based on observed residues (ATOM records): (download) 
    >1k4tA (A:)
qkwkwweeerypegikwkflehkgpvfappyeplpenvkfyydgkvmklspkaeevatff
akmldheyttkeifrknffkdwrkemtneekniitnlskcdftqmsqyfkaqtearkqms
keeklkikeenekllkeygfcimdnhkerianfkieppglfrgrgnhpkmgmlkrrimpe
diiincskdakvpspppghkwkevrhdnkvtwlvswteniqgsikyimlnpssrikgekd
wqkyetarrlkkcvdkirnqyredwkskemkvrqravalyfidklalragnekeegetad
tvgccslrvehinlhpeldgqeyvvefdflgkdsiryynkvpvekrvfknlqlfmenkqp
eddlfdrlntgilnkhlqdlmegltakvfrtynasitlqqqlkeltapdenipakilsyn
ranravailcnhqrappktfeksmmnlqtkidakkeqladarrdlksakadakvmkdakt
kkvveskkkavqrleeqlmklevqatdreenkqialgtsklnyldpritvawckkwgvpi
ekiynktqrekfawaidmadedyef