PDB entry 1k47

View 1k47 on RCSB PDB site
Description: Crystal Structure of the Streptococcus pneumoniae Phosphomevalonate Kinase (PMK)
Class: transferase
Keywords: Alpha/beta single domain belonging to the GHMP kinase superfamily, MvaK2, Structural Genomics, PSI, Protein Structure Initiative, New York SGX Research Center for Structural Genomics, NYSGXRC, TRANSFERASE
Deposited on 2001-10-05, released 2002-05-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.215
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47a1, d1k47a2, d1k47a3
  • Chain 'B':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47b1, d1k47b2, d1k47b3
  • Chain 'C':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47c1, d1k47c2, d1k47c3
  • Chain 'D':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47d1, d1k47d2, d1k47d3
  • Chain 'E':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47e1, d1k47e2, d1k47e3
  • Chain 'F':
    Compound: phosphomevalonate kinase
    Species: Streptococcus pneumoniae R6 [TaxId:171101]
    Gene: mvaK2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8DR49 (2-End)
      • cloning artifact (0-1)
      • modified residue (2)
      • modified residue (35)
      • modified residue (51)
      • modified residue (74)
      • modified residue (96)
      • modified residue (149)
      • modified residue (217)
    Domains in SCOPe 2.06: d1k47f1, d1k47f2, d1k47f3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1k47A (A:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47A (A:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1k47B (B:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47B (B:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1k47C (C:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47C (C:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1k47D (D:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47D (D:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1k47E (E:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47E (E:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1k47F (F:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmfdfavdlr
pnpdysliqetialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkal
lalynlsvdqnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeen
latvlerdwgfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvs
lvealeqgksekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdc
gialsfdaqstktlknrwadlgiellyqerighddks

    Sequence, based on observed residues (ATOM records): (download) 
    >1k47F (F:)
hmmiavktcgklywageyailepgqlalikdipiymraeiafsdsyriysdmnpdysliq
etialmgdflavrgqnlrpfslaiygkmeregkkfglgssgsvvvlvvkallalynlsvd
qnllfkltsavllkrgdngsmgdlaciaaedlvlyqsfdrqkvaawleeenlatvlerdw
gfsisqvkptlecdflvgwtkevavsshmvqqikqninqnfltssketvvslvealeqgk
sekiieqvevasklleglstdiytpllrqlkeasqdlqavakssgagggdcgialsfdaq
stktlknrwadlgiellyqeri