PDB entry 1k3a

View 1k3a on RCSB PDB site
Description: Structure of the Insulin-like Growth Factor 1 Receptor Kinase
Class: Transferase
Keywords: protein kinase, tyrosine kinase, tyrosine phosphorylation, protein-substrate complex, Transferase
Deposited on 2001-10-02, released 2001-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.212
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: insulin-like growth factor 1 receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08069 (0-298)
      • modified residue (173)
      • modified residue (177-178)
      • variant (254)
    Domains in SCOPe 2.07: d1k3aa_
  • Chain 'B':
    Compound: insulin receptor substrate 1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ACP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1k3aA (A:)
vpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerief
lneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpemennpvlapp
slskmiqmageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyr
kggkgllpvrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvme
gglldkpdncpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

    Sequence, based on observed residues (ATOM records): (download) 
    >1k3aA (A:)
vpdewevarekitmsrelgqgsfgmvyegvakgvvkdepetrvaiktvneaasmrerief
lneasvmkefnchhvvrllgvvsqgqptlvimelmtrgdlksylrslrpempslskmiqm
ageiadgmaylnankfvhrdlaarncmvaedftvkigdfgmtrdiyetdyyrkggkgllp
vrwmspeslkdgvfttysdvwsfgvvlweiatlaeqpyqglsneqvlrfvmegglldkpd
ncpdmllelmrmcwqynpkmrpsfleiissikeemepgfrevsfyyseenk

  • Chain 'B':
    No sequence available.