PDB entry 1k2d

View 1k2d on RCSB PDB site
Description: Crystal structure of the autoimmune MHC class II I-Au complexed with myelin basic protein 1-11 at 2.2A
Class: immune system
Keywords: crystal structure, MHC class II, I-Au, H-2u, autoimmune disease, unique register, experimental autoimmune encephalomyelitis, myelin basic protein
Deposited on 2001-09-26, released 2003-03-04
The last revision prior to the SCOP 1.73 freeze date was dated 2003-03-04, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.248
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: H-2 class II histocompatibility antigen, A-U alpha chain
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P14438 (10-End)
      • cloning artifact (7-9)
    Domains in SCOP 1.73: d1k2da1, d1k2da2
  • Chain 'B':
    Compound: H-2 class II histocompatibility antigen, A-U beta chain
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1k2db1, d1k2db2
  • Chain 'P':
    Compound: Myelin Basic Protein peptide with 8 residue linker peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • GB XP_040888 (4-End)
      • cloning artifact (1-3)
      • conflict (4)
  • Heterogens: NDG, NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1k2dA (A:)
hsrgeddieadhvgsygivvyqspgdigqytfefdgdelfyvdldkketiwmlpefaqlr
sfdpqgglqniatgkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdni
fppvinitwlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwglee
pvlkhwepe

    Sequence, based on observed residues (ATOM records): (download) 
    >1k2dA (A:)
ieadhvgsygivvyqspgdigqytfefdgdelfyvdldkketiwmlpefaqlrsfdpqgg
lqniatgkhnlgvltkrsnstpatneapqatvfpkspvllgqpntlicfvdnifppvini
twlrnsksvadgvyetsffvnrdysfhklsyltfipsdddiydckvehwgleepvlkhwe
pe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1k2dB (B:)
gdserhfvvqfqpfcyftngtqriryvtryiynreeylrfdsdvgeyravtelgrpdaey
ynkqylertraeldtvcrynyeetevptslrrleqpnvvislsrtealnhhntlvcsvtd
fypakikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehpslk
spitvewra

    Sequence, based on observed residues (ATOM records): (download) 
    >1k2dB (B:)
rhfvvqfqpfcyftngtqriryvtryiynreeylrfdsdvgeyravtelgrpdaeyynkq
ylertraeldtvcrynyeetevptslrrleqpnvvislsrtealnhhntlvcsvtdfypa
kikvrwfrngqeetvgvsstqlirngdwtfqvlvmlemtprrgevytchvehpslkspit
vewra

  • Chain 'P':
    No sequence available.