PDB entry 1jvq

View 1jvq on RCSB PDB site
Description: Crystal structure at 2.6A of the ternary complex between antithrombin, a P14-P8 reactive loop peptide, and an exogenous tetrapeptide
Class: blood clotting, hydrolase inhibitor
Keywords: loop-sheet polymer, beta-barrell
Deposited on 2001-08-31, released 2003-06-03
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.204
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: P14-P8 reactive loop peptide
    Species: synthetic, synthetic
  • Chain 'D':
    Compound: exogenous Cholecystokinin tetrapeptide
    Species: synthetic, synthetic
  • Chain 'I':
    Compound: antithrombin-III
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jvqi_
  • Chain 'L':
    Compound: antithrombin-III
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jvql_
  • Heterogens: NDG, NAG, ACE, NH2, HOH

PDB Chain Sequences:

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1jvqI (I:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jvqI (I:)
    vdictakprdipmnpmciyrspeeatnrrvwelskansrfattfyqhladskndndnifl
    splsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkankss
    klvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegri
    tdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkf
    ryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvv
    hmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevnee
    gsastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1jvqL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jvqL (L:)
    vdictakprdipmnpmciynrrvwelskansrfattfyqhladskndndniflsplsist
    afamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkankssklvsanr
    lfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritdvipse
    aineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrrvae
    gtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmprfri
    edgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegseaaas
    tavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv