PDB entry 1jum

View 1jum on RCSB PDB site
Description: Crystal structure of the multidrug binding transcriptional repressor QacR bound to the natural drug berberine
Class: transcription
Keywords: multidrug binding, berberine, plant alkaloid, natural drug, QacR, multidrug recognition, S. aureus, TRANSCRIPTION
Deposited on 2001-08-24, released 2001-12-12
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-06-16, with a file datestamp of 2009-06-12.
Experiment type: XRAY
Resolution: 2.98 Å
R-factor: 0.236
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hypothetical transcriptional regulator in qaca 5'region
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.05: d1juma1, d1juma2
  • Chain 'B':
    Compound: hypothetical transcriptional regulator in qaca 5'region
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.05: d1jumb1, d1jumb2
  • Chain 'D':
    Compound: hypothetical transcriptional regulator in qaca 5'region
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.05: d1jumd1, d1jumd2
  • Chain 'E':
    Compound: hypothetical transcriptional regulator in qaca 5'region
    Species: Staphylococcus aureus [TaxId:1280]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • engineered (71)
      • engineered (140)
    Domains in SCOPe 2.05: d1jume1, d1jume2
  • Heterogens: SO4, BER, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jumA (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jumA (A:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jumB (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jumB (B:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1jumD (D:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jumD (D:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1jumE (E:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jumE (E:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikaktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls