PDB entry 1jtc

View 1jtc on RCSB PDB site
Description: Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F)
Class: hormone/growth factor
Keywords: beta-trefoil, HORMONE/GROWTH FACTOR COMPLEX
Deposited on 2001-08-20, released 2001-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.197
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acidic fibroblast growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (49)
    Domains in SCOPe 2.08: d1jtca1, d1jtca2
  • Chain 'B':
    Compound: acidic fibroblast growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (49)
    Domains in SCOPe 2.08: d1jtcb1, d1jtcb2
  • Chain 'C':
    Compound: acidic fibroblast growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (49)
    Domains in SCOPe 2.08: d1jtcc1, d1jtcc2
  • Chain 'D':
    Compound: acidic fibroblast growth factor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05230
      • engineered (49)
    Domains in SCOPe 2.08: d1jtcd1, d1jtcd2
  • Heterogens: FMT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jtcA (A:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >1jtcA (A:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jtcB (B:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >1jtcB (B:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1jtcC (C:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >1jtcC (C:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1jtcD (D:)
hhhhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgev
yikstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkn
gsckrgprthygqkailflplpvssd

    Sequence, based on observed residues (ATOM records): (download) 
    >1jtcD (D:)
hhhhfnlppgnykkpkllycsngghflrilpdgtvdgtrdrsdqhiqfqlsaesvgevyi
kstetgqylamdtdgllygsqtpneeclflerleenhyntyiskkhaeknwfvglkkngs
ckrgprthygqkailflplpv