PDB entry 1jsc

View 1jsc on RCSB PDB site
Description: Crystal Structure of the Catalytic Subunit of Yeast Acetohydroxyacid Synthase: A target for Herbicidal Inhibitors
Class: lyase
Keywords: acetohydroxyacid synthase, acetolactate synthase, fad, thiamin diphosphate, herbicide inhibition, lyase
Deposited on 2001-08-17, released 2002-01-16
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.188
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetohydroxy-acid synthase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1jsca1, d1jsca2, d1jsca3
  • Chain 'B':
    Compound: acetohydroxy-acid synthase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Gene: ILV2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1jscb1, d1jscb2, d1jscb3
  • Heterogens: K, MG, 2HP, TPP, FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jscA (A:)
apsfnvdpleqpaepsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypgga
ilpvydaihnsdkfnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmada
fadgipmvvftgqvptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeia
tsgrpgpvlvdlpkdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlin
lakkpvlyvgagilnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgc
atanlavqnadliiavgarfddrvtgniskfapearraaaegrggiihfevspkninkvv
qtqiavegdattnlgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvi
kklskvandtgrhvivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqv
akpeslvididgdasfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehrysh
thqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvag
gsgldefinfdpeverqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jscA (A:)
pdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqga
ghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdafq
eadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnpi
ptkttlpsaqdefvmqsinkaadlinlakkpvlyvgagilnhadgprllkelsdraqipv
tttlqglgsfdqedpksldmlgmhgcatanlavqnadliiavgarfddrvtgniskfape
arraaaegrggiihfevspkninkvvqtqiavegdattnlgkmmskifpvkersewfaqi
nkwkkeypyaymeetpgskikpqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwr
nphtfitsgglgtmgyglpaaigaqvakpeslvididgdasfnmtltelssavqagtpvk
ililnneeshthqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpvllevevdk
k

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jscB (B:)
apsfnvdpleqpaepsklakklraepdmdtsfvgltggqifnemmsrqnvdtvfgypgga
ilpvydaihnsdkfnfvlpkheqgaghmaegyarasgkpgvvlvtsgpgatnvvtpmada
fadgipmvvftgqvptsaigtdafqeadvvgisrsctkwnvmvksveelplrineafeia
tsgrpgpvlvdlpkdvtaailrnpiptkttlpsnalnqltsraqdefvmqsinkaadlin
lakkpvlyvgagilnhadgprllkelsdraqipvtttlqglgsfdqedpksldmlgmhgc
atanlavqnadliiavgarfddrvtgniskfapearraaaegrggiihfevspkninkvv
qtqiavegdattnlgkmmskifpvkersewfaqinkwkkeypyaymeetpgskikpqtvi
kklskvandtgrhvivttgvgqhqmwaaqhwtwrnphtfitsgglgtmgyglpaaigaqv
akpeslvididgdasfnmtltelssavqagtpvkililnneeqgmvtqwqslfyehrysh
thqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpvllevevdkkvpvlpmvag
gsgldefinfdpeverqqtelrhkrtggkh

    Sequence, based on observed residues (ATOM records): (download) 
    >1jscB (B:)
epdmdtsfvgltggqifnemmsrqnvdtvfgypggailpvydaihnsdkfnfvlpkheqg
aghmaegyarasgkpgvvlvtsgpgatnvvtpmadafadgipmvvftgqvptsaigtdaf
qeadvvgisrsctkwnvmvksveelplrineafeiatsgrpgpvlvdlpkdvtaailrnp
iptkttlpsnaltsraqdefvmqsinkaadlinlakpvlyvgagilnhadgprllkelsd
raqipvtttlqglgsfdqedpksldmlgmhgcatanlavqnadliiavgarfddrvtgni
skfapearraaiihfevspkninkvvqtqiavegdattnlgkmmskifpvrsewfaqink
wkkeyeetpgskikpqtvikklskvandtgrhvivttgvgqhqmwaaqhwtwrnphtfit
sgglgtmgyglpaaigaqvakpeslvididgdasfnmtltelssavqagtpvkililnne
eqgmvtqwqslfehryshthqlnpdfiklaeamglkglrvkkqeeldaklkefvstkgpv
llevevdkkv