PDB entry 1jr1

View 1jr1 on RCSB PDB site
Description: Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid
Class: oxidoreductase
Keywords: dehydrogenase, impd, impdh, guanine nucleotide synthesis, mycophenolic acid, mpa, oxidoreductase
Deposited on 2001-08-09, released 2001-09-05
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.217
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: Cricetulus griseus [TaxId:10029]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1jr1a1, d1jr1a4
  • Chain 'B':
    Compound: Inosine-5'-monophosphate dehydrogenase 2
    Species: Cricetulus griseus [TaxId:10029]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1jr1b1
  • Heterogens: K, IMP, MOA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jr1A (A:)
madylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkit
lktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvv
lspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdrfleeimt
kredlvvapagitlkeaneilqrskkgklpivnendelvaiiartdlkknrdyplaskda
kkqllcgaaigtheddkyrldllalagvdvvvldssqgnsifqinmikymkekypnlqvi
ggnvvtaaqaknlidagvdalrvgmgcgsicitqevlacgrpqatavykvseyarrfgvp
viadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldam
dkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvr
ammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records): (download) 
    >1jr1A (A:)
gltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvsspmdtvtea
gmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvvdrvrfeakmgsrlvim
tkredlvvapagitlkeaneilqrsklpivnendelvaiiartdlkknrdyplaskdakk
qllcgaaigtheddkyrldllalagvdvvvldssqgnsifqinmikymkekypnlqvigg
nvvtaaqaknlidagvdalrvgmgcgsicitqevlacgrpqatavykvseyarrfgvpvi
adggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamik
vaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvrammysgelkfekrtssaq
veggvhslhsyekrlf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jr1B (B:)
madylisggtsyvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkit
lktplvsspmdtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqgfitdpvv
lspkdrvrdvfeakarhgfcgipitdtgrmgsrlvgiissrdidflkeeehdrfleeimt
kredlvvapagitlkeaneilqrskkgklpivnendelvaiiartdlkknrdyplaskda
kkqllcgaaigtheddkyrldllalagvdvvvldssqgnsifqinmikymkekypnlqvi
ggnvvtaaqaknlidagvdalrvgmgcgsicitqevlacgrpqatavykvseyarrfgvp
viadggiqnvghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldam
dkhlssqnryfseadkikvaqgvsgavqdkgsihkfvpyliagiqhscqdigaksltqvr
ammysgelkfekrtssaqveggvhslhsyekrlf

    Sequence, based on observed residues (ATOM records): (download) 
    >1jr1B (B:)
syvpddgltaqqlfncgdgltyndflilpgyidftadqvdltsaltkkitlktplvsspm
dtvteagmaiamaltggigfihhnctpefqanevrkvkkyeqyplaskdakkqllcgaai
gtheddkyrldllalagvdvvvldssqgnsifqinmikymkekypnlqviggnvvtaaqa
knlidagvdalrvgmgcgsicitqevlacgrpqatavykvseyarrfgvpviadggiqnv
ghiakalalgastvmmgsllaatteapgeyffsdgirlkkyrgmgsldamikvaqgvsga
vqdkgsihkfvpyliagiqhscqdigaksltqvrammysgelkfekrtssaqveggvhsl
hsyekrlf