PDB entry 1jqd

View 1jqd on RCSB PDB site
Description: Crystal Structure Analysis of Human Histamine Methyltransferase (Thr105 Polymorphic Variant) Complexed with AdoHcy and Histamine
Class: transferase
Keywords: Classic methyltransferase fold, protein-substrate-cofactor complex, TRANSFERASE
Deposited on 2001-08-06, released 2002-08-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.28 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histamine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: HNMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1jqda_
  • Chain 'B':
    Compound: Histamine N-methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: HNMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1jqdb_
  • Heterogens: SAH, HSM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1jqdA (A:)
    massmrslfsdhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsig
    ggageidlqilskvqaqypgvcinnevvepsaeqiakykelvaktsnlenvkfawhkets
    seyqsrmlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwd
    klwkkygsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdll
    wdfltetcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jqdA (A:)
    mrslfhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsigggagei
    dlqilskvqaqypgvcinnevvepsaeqiakykelvaktsnlenvkfawhketsseyqsr
    mlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwdklwkky
    gsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdllwdflte
    tcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1jqdB (B:)
    massmrslfsdhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsig
    ggageidlqilskvqaqypgvcinnevvepsaeqiakykelvaktsnlenvkfawhkets
    seyqsrmlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwd
    klwkkygsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdll
    wdfltetcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jqdB (B:)
    mrslfsdhgkyvesfrrflnhstehqcmqefmdkklpgiigrigdtkseikilsigggag
    eidlqilskvqaqypgvcinnevvepsaeqiakykelvaktsnlenvkfawhketsseyq
    srmlekkelqkwdfihmiqmlyyvkdipatlkffhsllgtnakmliivvsgssgwdklwk
    kygsrfpqddlcqyitsddltqmldnlglkyecydllstmdisdcfidgnengdllwdfl
    tetcnfnatappdlraelgkdlqepefsakkegkvlfnntlsfiviea