PDB entry 1jpw

View 1jpw on RCSB PDB site
Description: Crystal Structure of a Human Tcf-4 / beta-Catenin Complex
Class: cell adhesion
Keywords: beta-catenin, tcf, tcf4, colon cancer, armadillo repeat, transcription factor, CELL ADHESION
Deposited on 2001-08-03, released 2001-12-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-31, with a file datestamp of 2018-01-26.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-catenin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwa_
  • Chain 'B':
    Compound: beta-catenin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwb_
  • Chain 'C':
    Compound: beta-catenin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwc_
  • Chain 'D':
    Compound: transcription factor 7-like 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwd_
  • Chain 'E':
    Compound: transcription factor 7-like 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwe_
  • Chain 'F':
    Compound: transcription factor 7-like 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1jpwf_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jpwA (A:)
mgshavvnlinyqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimr
spqmvsaivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvds
vlfyaittlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqe
skliilasggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhl
tdpsqrlvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcn
nyknkmmvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyg
lpvvvkllhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrr
tsmggtqqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieni
qrvaagvlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdy

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwA (A:)
raipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqntndvet
arctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllhqegak
mavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalvnimrt
ytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtlrnlsd
aatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggiealvrt
vlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwplikat
vglirnlalcpanhaplreqgaiprlvqllvrahqdtqrfvegvrmeeivegctgalhil
ardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieaegatapl
tellhsrnegvatyaaavlfrm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1jpwB (B:)
mgshavvnlinyqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimr
spqmvsaivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvds
vlfyaittlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqe
skliilasggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhl
tdpsqrlvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcn
nyknkmmvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyg
lpvvvkllhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrr
tsmggtqqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieni
qrvaagvlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdy

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwB (B:)
raipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqntndvet
arctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllhqegak
mavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalvnimrt
ytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtlrnlsd
aatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggiealvrt
vlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwplikat
vglirnlalcpanhaplreqgaiprlvqllvrahqdtqrfvegvrmeeivegctgalhil
ardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieaegatapl
tellhsrnegvatyaaavlfrm

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1jpwC (C:)
mgshavvnlinyqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimr
spqmvsaivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvds
vlfyaittlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqe
skliilasggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhl
tdpsqrlvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcn
nyknkmmvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyg
lpvvvkllhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrr
tsmggtqqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieni
qrvaagvlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdy

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwC (C:)
raipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqntndvet
arctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllhqegak
mavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalvnimrt
ytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtlrnlsd
aatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggiealvrt
vlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwplikat
vglirnlalcpanhaplreqgaiprlvqllvrahqdtqrfvegvrmeeivegctgalhil
ardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieaegatapl
tellhsrnegvatyaaavlfrm

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1jpwD (D:)
gsggddlgandelisfkdegeqeekssenssaerdladvksslvneset

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwD (D:)
gandelisfkdegdladvksslvn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1jpwE (E:)
gsggddlgandelisfkdegeqeekssenssaerdladvksslvneset

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwE (E:)
gandelisfkdegdladvksslvn

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1jpwF (F:)
gsggddlgandelisfkdegeqeekssenssaerdladvksslvneset

    Sequence, based on observed residues (ATOM records): (download) 
    >1jpwF (F:)
gandelisfkdegdladvksslvn