PDB entry 1jph

View 1jph on RCSB PDB site
Description: Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase
Class: lyase
Keywords: Heme Biosynthesis, LYASE
Deposited on 2001-08-02, released 2001-12-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.202
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uroporphyrinogen decarboxylase
    Species: Homo sapiens [TaxId:9606]
    Gene: UROD
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06132
      • engineered (280)
    Domains in SCOPe 2.08: d1jpha_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jphA (A:)
mghhhhhhhhhhssghiegrhmeanglgpqgfpelkndtflraawgeetdytpvwcmrqa
grylpefretraaqdffstcrspeacceltlqplrrfpldaaiifsdilvvpqalgmevt
mvpgkgpsfpeplreeqdlerlrdpevvaselgyvfqaitltrqrlagrvpligfagapw
tlmtymvegggsstmaqakrwlyqrpqashqllriltdalvpylvgqvvagaqalqlfes
haghlgpqlfnkfalpyirdvakqvkarlreaglapvpmitfakdghfaleelaqagyev
vgldwtvapkkarecvgktvtlqgnldpcalyaseeeigqlvkqmlddfgphryianlgh
glypdmdpehvgafvdavhkhsrllrqn

    Sequence, based on observed residues (ATOM records): (download) 
    >1jphA (A:)
gfpelkndtflraawgeetdytpvwcmrqagrylpefretraaqdffstcrspeaccelt
lqplrrfpldaaiifsdilvvpqalgmevtmvpgkgpsfpeplreeqdlerlrdpevvas
elgyvfqaitltrqrlagrvpligfagapwtlmtymvegggsstmaqakrwlyqrpqash
qllriltdalvpylvgqvvagaqalqlfeshaghlgpqlfnkfalpyirdvakqvkarlr
eaglapvpmitfakdghfaleelaqagyevvgldwtvapkkarecvgktvtlqgnldpca
lyaseeeigqlvkqmlddfgphryianlghglypdmdpehvgafvdavhkhsrllrq