PDB entry 1jmo

View 1jmo on RCSB PDB site
Description: Crystal Structure of the Heparin Cofactor II-S195A Thrombin Complex
Class: blood clotting
Keywords: serpin, thrombin, protease, inhibition, inhibitor
Deposited on 2001-07-19, released 2002-08-30
The last revision prior to the SCOP 1.73 freeze date was dated 2002-08-30, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.205
AEROSPACI score: -1.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heparin cofactor II
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05546 (Start-479)
      • modified residue (59)
      • modified residue (72)
    Domains in SCOP 1.73: d1jmoa_
  • Chain 'H':
    Compound: Thrombin, heavy chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (Start-259)
      • engineered (205)
    Domains in SCOP 1.73: d1jmo.1
  • Chain 'L':
    Compound: Thrombin, light chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1jmo.1
  • Heterogens: NAG, NDG, NA, MPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1jmoA (A:)
gskgpldqlekggetaqsadpqweqlnnknlsmpllpadfhkentvtndwipegeedddy
ldlekifsedddyidivdslsvsptdsdvsagnilqlfhgksriqrlnilnakfafnlyr
vlkdqvntfdnifiapvgistamgmislglkgetheqvhsilhfkdfvnasskyeittih
nlfrklthrlfrrnfgytlrsvndlyiqkqfpilldfktkvreyyfaeaqiadfsdpafi
sktnnhimkltkglikdalenidpatqmmilnciyfkgswvnkfpvemthnhnfrlnere
vvkvsmmqtkgnflaandqeldcdilqleyvggismlivvphkmsgmktleaqltprvve
rwqksmtnrtrevllpkfkleknynlveslklmgirmlfdkngnmagisdqriaidlfkh
qgtitvneegtqattvttvgfmplstqvrftvdrpflfliyehrtscllfmgrvanpsrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1jmoA (A:)
geedddyldlekifsedddyidivdslsvsptdsdvsagnilqlfhgksriqrlnilnak
fafnlyrvlkdqvntfdnifiapvgistamgmislglkgetheqvhsilhfkdfvnassk
yeittihnlfrklthrlfrrnfgytlrsvndlyiqkqfpilldfktkvreyyfaeaqiad
fsdpafisktnnhimkltkglikdalenidpatqmmilnciyfkgswvnkfpvemthnhn
frlnerevvkvsmmqtkgnflaandqeldcdilqleyvggismlivvphkmsgmktleaq
ltprvverwqksmtnrtrevllpkfkleknynlveslklmgirmlfdkngnmagisdqri
aidlfkhqgtitvneegtqattvttvgfmplstqvrftvdrpflfliyehrtscllfmgr
vanpsrs

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1jmoH (H:)
rivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendl
lvrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvc
lpdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstri
ritdnmfcagykpdegkrgdacegdaggpfvmkspfnnrwyqmgivswgegcdrdgkygf
ythvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1jmoH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdaggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1jmoL (L:)
tatseyqtffnprtfgsgeadcglrplfekksledkterellesyidg

    Sequence, based on observed residues (ATOM records): (download) 
    >1jmoL (L:)
atseyqtffnprtfgsgeadcglrplfekksledkterellesyidg