PDB entry 1jg0

View 1jg0 on RCSB PDB site
Description: Crystal structure of Escherichia coli thymidylate synthase complexed with 2'-deoxyuridine-5'-monophosphate and N,O-didansyl-L-tyrosine
Class: transferase
Keywords: thymidylate synthase, didansyl tyrosine, TRANSFERASE
Deposited on 2001-06-22, released 2002-02-08
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.212
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Thymidylate synthase
    Species: Escherichia coli [TaxId:562]
    Gene: Esherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A884 (0-End)
      • modified residue (0)
      • conflict (20)
      • conflict (106)
    Domains in SCOPe 2.06: d1jg0a_
  • Chain 'B':
    Compound: Thymidylate synthase
    Species: Escherichia coli [TaxId:562]
    Gene: Esherichia coli
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A884 (0-End)
      • modified residue (0)
      • conflict (20)
      • conflict (106)
    Domains in SCOPe 2.06: d1jg0b_
  • Heterogens: UMP, DDT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1jg0A (A:)
    mkqylelmqkvldegtqkndatgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
    wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgahidqittvlnqlk
    ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
    yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
    dyrfedfeiegydphpgikapvai
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jg0A (A:)
    mkqylelmqkvldegtqkndatgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
    wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgahidqittvlnqlk
    ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
    yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
    dyrfedfeiegydphpgikapva
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1jg0B (B:)
    mkqylelmqkvldegtqkndatgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
    wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgahidqittvlnqlk
    ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
    yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
    dyrfedfeiegydphpgikapvai
    

    Sequence, based on observed residues (ATOM records): (download)
    >1jg0B (B:)
    mkqylelmqkvldegtqkndatgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
    wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgahidqittvlnqlk
    ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
    yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
    dyrfedfeiegydphpgikapva