PDB entry 1izh
View 1izh on RCSB PDB site
Description: Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants
Class: hydrolase
Keywords: HIV-1 proteinase, potent inhibitor, subsite binding
Deposited on
2002-10-02, released
2002-12-23
The last revision prior to the SCOP 1.75 freeze date was dated
2002-12-23, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.181
AEROSPACI score: 0.6
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: proteinase
Species: Human immunodeficiency virus 1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1izha_ - Chain 'B':
Compound: proteinase
Species: Human immunodeficiency virus 1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1izhb_ - Heterogens: Q50, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1izhA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1izhB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemnlpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf