PDB entry 1iyo

View 1iyo on RCSB PDB site
Description: Toho-1 beta-Lactamase In Complex With Cefotaxime
Class: hydrolase
Keywords: extended-spectrum, ESBL, BETA-LACTAMASE, ACYL-ENZYME, cefotaxime, complex, HYDROLASE
Deposited on 2002-09-04, released 2002-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-03-15, with a file datestamp of 2017-03-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toho-1 beta-lactamase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q47066 (Start-261)
      • engineered (139)
    Domains in SCOPe 2.08: d1iyoa_
  • Heterogens: SO4, CEF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1iyoA (A:)
ansvqqqlealekssggrlgvalintadnsqilyraderfamcstskvmaaaavlkqses
dkhllnqrveikksdlvnynpiaekhvngtmtlaelgaaalqysdntamnkliahlggpd
kvtafarslgdetfrldrtaptlntaipgdprdtttplamaqtlknltlgkalaetqraq
lvtwlkgnttgsasiraglpkswvvgdktgsgdygttndiaviwpenhaplvlvtyftqp
eqkaerrrdilaaaakivthgf

    Sequence, based on observed residues (ATOM records): (download) 
    >1iyoA (A:)
svqqqlealekssggrlgvalintadnsqilyraderfamcstskvmaaaavlkqsesdk
hllnqrveikksdlvnynpiaekhvngtmtlaelgaaalqysdntamnkliahlggpdkv
tafarslgdetfrldrtaptlntaipgdprdtttplamaqtlknltlgkalaetqraqlv
twlkgnttgsasiraglpkswvvgdktgsgdygttndiaviwpenhaplvlvtyftqpeq
kaerrrdilaaaakivthgf