PDB entry 1it6

View 1it6 on RCSB PDB site
Description: crystal structure of the complex between calyculin a and the catalytic subunit of protein phosphatase 1
Class: hydrolase
Keywords: hydrolase-inhibitor complex
Deposited on 2002-01-09, released 2002-05-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine protein phosphatase 1 gamma (pp1-gamma) catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1it6a_
  • Chain 'B':
    Compound: serine/threonine protein phosphatase 1 gamma (pp1-gamma) catalytic subunit
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1it6b_
  • Heterogens: MN, CYU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1it6A (A:)
madldklnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplk
icgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffl
lrgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdl
qsmeqirrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhd
ldlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpae
kkkpnatrpvtpprgmitkqakk

    Sequence, based on observed residues (ATOM records): (download) 
    >1it6A (A:)
lnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1it6B (B:)
madldklnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplk
icgdihgqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffl
lrgnhecasinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdl
qsmeqirrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhd
ldlicrahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpae
kkkpnatrpvtpprgmitkqakk

    Sequence, based on observed residues (ATOM records): (download) 
    >1it6B (B:)
lnidsiiqrllevrgskpgknvqlqeneirglclksreiflsqpilleleaplkicgdih
gqyydllrlfeyggfppesnylflgdyvdrgkqsleticlllaykikypenffllrgnhe
casinriygfydeckrryniklwktftdcfnclpiaaivdekifcchgglspdlqsmeqi
rrimrptdvpdqgllcdllwsdpdkdvlgwgendrgvsftfgaevvakflhkhdldlicr
ahqvvedgyeffakrqlvtlfsapnycgefdnagammsvdetlmcsfqilkpa