PDB entry 1isr

View 1isr on RCSB PDB site
Description: Crystal Structure of Metabotropic Glutamate Receptor Subtype 1 Complexed with Glutamate and Gadolinium Ion
Class: signaling protein
Keywords: signal transduction, neurotransmitter, g protein coupled receptor, agonist, gadolinium ion, signaling protein
Deposited on 2001-12-21, released 2002-03-13
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 4 Å
R-factor: 0.237
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: metabotropic glutamate receptor subtype 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1isra_
  • Heterogens: GLU, GD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1isrA (A:)
ssqrsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinad
pvllpnitlgseirdscwhssvaleqsiefirdslisirdekdglnrclpdgqtlppgrt
kkpiagvigpgsssvaiqvqnllqlfdipqiaysatsidlsdktlykyflrvvpsdtlqa
ramldivkrynwtyvsavhtegnygesgmdafkelaaqeglciahsdkiysnageksfdr
llrklrerlpkarvvvcfcegmtvrgllsamrrlgvvgefsligsdgwadrdeviegyev
eanggitiklqspevrsfddyflklrldtntrnpwfpefwqhrfqcrlpghllenpnfkk
vctgnesleenyvqdskmgfvinaiyamahglqnmhhalcpghvglcdamkpidgrklld
flikssfvgvsgeevwfdekgdapgrydimnlqyteanrydyvhvgtwhegvlniddyki
qmnksgmvrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1isrA (A:)
rsvarmdgdviigalfsvhhqppaekvperkcgeireqygiqrveamfhtldkinadpvl
lpnitlgseirdscwhssvaleqsiefirkpiagvigpgsssvaiqvqnllqlfdipqia
ysatsidlsdktlykyflrvvpsdtlqaramldivkrynwtyvsavhtegnygesgmdaf
kelaaqeglciahsdkiysnageksfdrllrklrerlpkarvvvcfcegmtvrgllsamr
rlgvvgefsligsdgwadrdeviegyeveanggitiklqspevrsfddyflklrldtntr
npwfpefwqhrfqcrlpghllenpnfkkvctgnesleenyvqdskmgfvinaiyamahgl
qnmhhalcpghvglcdamkpidgrklldflikssfvgvsgeevwfdekgdapgrydimnl
qyteanrydyvhvgtwhegvlniddyki