PDB entry 1io4

View 1io4 on RCSB PDB site
Description: crystal structure of runx-1/aml1/cbfalpha runt domain-cbfbeta core domain heterodimer and c/ebpbeta bzip homodimer bound to a DNA fragment from the csf-1r promoter
Class: transcription/DNA
Keywords: protein-DNA complex, transcription factor, bzip, runx, runt, c/ebp, cbf, core binding factor, aml1, aml, transcription/DNA complex
Deposited on 2001-01-10, released 2001-03-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.247
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: caat/enhancer binding protein beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1io4a_
  • Chain 'B':
    Compound: caat/enhancer binding protein beta
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1io4b_
  • Chain 'C':
    Compound: runt-related transcription factor 1
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1io4c_
  • Chain 'D':
    Compound: core-binding factor, beta subunit
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1io4d_
  • Chain 'E':
    Compound: csf-1r promoter
  • Chain 'F':
    Compound: csf-1r promoter
  • Heterogens: AU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1io4A (A:)
vkskakktvdkhsdeykirrernniavrksrdkakmrnletqhkvleltaenerlqkkve
qlsrelstlrnlfkqlpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1io4A (A:)
khsdeykirrernniavrksrdkakmrnletqhkvleltaenerlqkkveqlsrelstlr
nlf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1io4B (B:)
vkskakktvdkhsdeykirrernniavrksrdkakmrnletqhkvleltaenerlqkkve
qlsrelstlrnlfkqlpe

    Sequence, based on observed residues (ATOM records): (download) 
    >1io4B (B:)
ktvdkhsdeykirrernniavrksrdkakmrnletqhkvleltaenerlqkkveqlsrel
stlrnlfkql

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1io4C (C:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgpreprrh
rqk

    Sequence, based on observed residues (ATOM records): (download) 
    >1io4C (C:)
gelvrtdspnflcsvlpthwrcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrn
ataamknqvarfndlrfvgrsgrgksftltitvftnppqvatyhraikitvdgpreprrh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1io4D (D:)
mprvvpdqrskfeneeffrklsreceikytgfrdrpheerqtrfqnacrdgrseiafvat
gtnlslqffpaswqgeqrqtpsreyvdlereagkvylkapmilngvcviwkgwidlhrld
gmgclefdeeraqqedalaqq

    Sequence, based on observed residues (ATOM records): (download) 
    >1io4D (D:)
prvvpdqrskfeneeffrklsreceikytgfrdrpheerqtrfqnacrdgrseiafvatg
tnlslqffpsreyvdlereagkvylkapmilngvcviwkgwidlhrldgmgclefdeera
qqedalaq

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.