PDB entry 1im9

View 1im9 on RCSB PDB site
Description: Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1 bound to its MHC ligand HLA-Cw4
Class: immune system
Keywords: protein-protein complex, immunoglobulin domain, antiparallel beta sheet, alpha helix
Deposited on 2001-05-10, released 2001-05-30
The last revision prior to the SCOP 1.75 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.213
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen, cw-4 cw*0401 alpha chain
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1im9a1, d1im9a2
  • Chain 'B':
    Compound: beta-2 microglobulin
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • cloning artifact (0)
    Domains in SCOP 1.75: d1im9b_
  • Chain 'C':
    Compound: HLA-Cw4-specific peptide
    Species: synthetic, synthetic
    Gene:
  • Chain 'D':
    Compound: killer cell immunoglobulin-like receptor 2dl1
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1im9d1, d1im9d2
  • Chain 'E':
    Compound: hla class I histocompatibility antigen, cw-4 cw*0401 alpha chain
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1im9e1, d1im9e2
  • Chain 'F':
    Compound: beta-2 microglobulin
    Species: HOMO SAPIENS
    Gene:
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • cloning artifact (0)
    Domains in SCOP 1.75: d1im9f_
  • Chain 'G':
    Compound: HLA-Cw4-specific peptide
    Species: synthetic, synthetic
    Gene:
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1im9A (A:)
    mgshsmryfstsvswpgrgeprfiavgyvddtqfvrfdsdaasprgeprepwveqegpey
    wdretqkykrqaqadrvnlrklrgyynqsedgshtlqrmfgcdlgpdgrllrgynqfayd
    gkdyialnedlrswtaadtaaqitqrkweaareaeqrraylegtcvewlrrylengketl
    qraehpkthvthhpvsdheatlrcwalgfypaeitltwqwdgedqtqdtelvetrpagdg
    tfqkwaavvvpsgeeqrytchvqheglpepltlrwk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1im9A (A:)
    gshsmryfstsvswpgrgeprfiavgyvddtqfvrfdsdaasprgeprepwveqegpeyw
    dretqkykrqaqadrvnlrklrgyynqsedgshtlqrmfgcdlgpdgrllrgynqfaydg
    kdyialnedlrswtaadtaaqitqrkweaareaeqrraylegtcvewlrrylengketlq
    raehpkthvthhpvsdheatlrcwalgfypaeitltwqwdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpepltlrwk
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1im9B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1im9D (D:)
    mhegvhrkpsllahpgplvkseetvilqcwsdvmfehfllhregmfndtlrligehhdgv
    skanfsisrmtqdlagtyrcygsvthspyqvsapsdpldiviiglyekpslsaqpgptvl
    agenvtlscssrssydmyhlsregeaherrlpagpkvngtfqadfplgpathggtyrcfg
    sfhdspyewskssdpllvsvtgnpsnswpsptepssktgnprhlh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1im9D (D:)
    rkpsllahpgplvkseetvilqcwsdvmfehfllhregmfndtlrligehhdgvskanfs
    isrmtqdlagtyrcygsvthspyqvsapsdpldiviiglyekpslsaqpgptvlagenvt
    lscssrssydmyhlsregeaherrlpagpkvngtfqadfplgpathggtyrcfgsfhdsp
    yewskssdpllvsvt
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1im9E (E:)
    mgshsmryfstsvswpgrgeprfiavgyvddtqfvrfdsdaasprgeprepwveqegpey
    wdretqkykrqaqadrvnlrklrgyynqsedgshtlqrmfgcdlgpdgrllrgynqfayd
    gkdyialnedlrswtaadtaaqitqrkweaareaeqrraylegtcvewlrrylengketl
    qraehpkthvthhpvsdheatlrcwalgfypaeitltwqwdgedqtqdtelvetrpagdg
    tfqkwaavvvpsgeeqrytchvqheglpepltlrwk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1im9E (E:)
    gshsmryfstsvswpgrgeprfiavgyvddtqfvrfdsdaasprgeprepwveqegpeyw
    dretqkykrqaqadrvnlrklrgyynqsedgshtlqrmfgcdlgpdgrllrgynqfaydg
    kdyialnedlrswtaadtaaqitqrkweaareaeqrraylegtcvewlrrylengketlq
    raehpkthvthhpvsdheatlrcwalgfypaeitltwqwdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpepltlrwk
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1im9F (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'G':
    No sequence available.