PDB entry 1ikf
View 1ikf on RCSB PDB site
Description: a conformation of cyclosporin a in aqueous environment revealed by the x-ray structure of a cyclosporin-fab complex
Class: immune system/immunosuppressant
Keywords: immune system-immunosuppressant complex, fab-cyclosporin complex, cyclosporin a, immunosuppressant
Deposited on
1993-12-09, released
1995-03-31
The last revision prior to the SCOPe 2.04 freeze date was dated
2011-07-27, with a file datestamp of
2011-07-22.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.164
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'C':
Compound: cyclosporin a
Species: Tolypocladium inflatum, synthetic [TaxId:29910]
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: igg1-kappa r45-45-11 fab (heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1ikfh1, d1ikfh2 - Chain 'L':
Compound: igg1-kappa r45-45-11 fab (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.04: d1ikfl1, d1ikfl2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'C':
No sequence available.
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1ikfH (H:)
evklvesggglvqpggslklscatsgftfsdyymywvrqnsekrlewvafisngggsafy
adivkgrftisrdnakntlylqmsrlksedtamyyctrhtlydtlygnypvwfadwgqgt
lvtvsaakttppsvyplapgsaaqtnsmvtlgclvkgyfpepvtvtwnsgslssgvhtfp
avlqsdlytlsssvtvpsssrpsetvtcnvahpasstkvdkkivprdc
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1ikfL (L:)
diqmtqttsslsaslgdrvtiscrasqdistylnwyqqkpdgtvkllifytsrlrsgvps
rfsgsgsgtdysltisnleqediatyfcqqgsripptfgggtkleilradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnraac