PDB entry 1igx

View 1igx on RCSB PDB site
Description: Crystal Structure of Eicosapentanoic Acid Bound in the Cyclooxygenase Channel of Prostaglandin Endoperoxide H Synthase-1.
Class: oxidoreductase
Keywords: membrane protein, fatty acid, eicosapentanoic acid, oxidoreductase, peroxidase, dioxygenase
Deposited on 2001-04-18, released 2001-12-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prostaglandin endoperoxide h synthase-1
    Species: Ovis aries [TaxId:9940]
    Database cross-references and differences (RAF-indexed):
    • GB AAA31511
    Domains in SCOPe 2.08: d1igxa1, d1igxa2
  • Heterogens: BOG, BGC, COH, EPA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1igxA (A:)
    adpgapapvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrp
    spsfihfllthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsn
    vsyytrilpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqh
    fthqffktsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevypp
    sveeapvlmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwg
    deqlfqtarliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnql
    yhwhplmpdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhi
    lhvavdvikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefy
    pglllekchpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatl
    kklvclntktcpyvsfhvpdprqedrpgverpptel
    

    Sequence, based on observed residues (ATOM records): (download)
    >1igxA (A:)
    pvnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipeiwtwlrttlrpspsfihf
    llthgrwlwdfvnatfirdtlmrlvltvrsnlipspptyniahdyiswesfsnvsyytri
    lpsvprdcptpmgtkgkkqlpdaeflsrrfllrrkfipdpqgtnlmfaffaqhfthqffk
    tsgkmgpgftkalghgvdlghiygdnlerqyqlrlfkdgklkyqmlngevyppsveeapv
    lmhyprgippqsqmavgqevfgllpglmlyatiwlrehnrvcdllkaehptwgdeqlfqt
    arliligetikivieeyvqqlsgyflqlkfdpellfgaqfqyrnriamefnqlyhwhplm
    pdsfrvgpqdysyeqflfntsmlvdygvealvdafsrqpagrigggrnidhhilhvavdv
    ikesrvlrlqpfneyrkrfgmkpytsfqeltgekemaaeleelygdidalefypglllek
    chpnsifgesmiemgapfslkgllgnpicspeywkastfggevgfnlvktatlkklvcln
    tktcpyvsfhvpd