PDB entry 1igw

View 1igw on RCSB PDB site
Description: Crystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia coli
Class: lyase
Keywords: beta barrel, lyase
Deposited on 2001-04-18, released 2001-09-05
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.187
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: isocitrate lyase
    Species: Escherichia coli [TaxId:562]
    Gene: aceA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9G6
      • engineered (218)
    Domains in SCOPe 2.03: d1igwa_
  • Chain 'B':
    Compound: isocitrate lyase
    Species: Escherichia coli [TaxId:562]
    Gene: aceA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9G6
      • engineered (218)
    Domains in SCOPe 2.03: d1igwb_
  • Chain 'C':
    Compound: isocitrate lyase
    Species: Escherichia coli [TaxId:562]
    Gene: aceA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9G6
      • engineered (218)
    Domains in SCOPe 2.03: d1igwc_
  • Chain 'D':
    Compound: isocitrate lyase
    Species: Escherichia coli [TaxId:562]
    Gene: aceA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A9G6
      • engineered (218)
    Domains in SCOPe 2.03: d1igwd_
  • Heterogens: HG, MG, PYR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1igwA (A:)
mktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhge
skkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpav
verinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieaga
aavhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadl
itsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarr
faqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwf
nmfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqggts
svtaltgsteesqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1igwA (A:)
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvkkcgkvlvptqeaiqklvaarlcadvtgvptllvartdadaadlitsdc
dpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrfaqai
hakypgkllayncsfqqqlsdmgykfqfitlagihsmwfnmfdlanayaqgegmkhyvek
vqqpefaaakdgytfvshqqevgtgyfdkvttiiqg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1igwB (B:)
mktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhge
skkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpav
verinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieaga
aavhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadl
itsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarr
faqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwf
nmfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqggts
svtaltgsteesqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1igwB (B:)
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvkkgkvlvptqeaiqklvaarlcadvtgvptllvartdadaadlitsdcd
pydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrfaqaih
akypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwfnmfdla
nayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1igwC (C:)
mktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhge
skkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpav
verinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieaga
aavhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadl
itsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarr
faqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwf
nmfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqggts
svtaltgsteesqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1igwC (C:)
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadli
tsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrf
aqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwfn
mfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1igwD (D:)
mktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhge
skkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpav
verinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieaga
aavhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadl
itsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarr
faqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwf
nmfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqggts
svtaltgsteesqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1igwD (D:)
ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges
kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv
erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa
avhfedqlasvgkvlvptqeaiqklvaarlcadvtgvptllvartdadaadlitsdcdpy
dsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrfaqaihak
ypgkllayncspsfnwddktiasfqqqlsdmgykfqfitlagihsmwfnmfdlanayaqg
egmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqg