PDB entry 1iar

View 1iar on RCSB PDB site
Description: interleukin-4 / receptor alpha chain complex
Class: cytokine/receptor
Keywords: cytokine receptor, interleukin-4, cytokine-receptor complex
Deposited on 1999-02-25, released 2000-03-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein (interleukin-4)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1iara_
  • Chain 'B':
    Compound: protein (interleukin-4 receptor alpha chain)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24394 (0-End)
      • engineered mutation (181)
      • engineered mutation (0)
    Domains in SCOPe 2.08: d1iarb1, d1iarb2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1iarA (A:)
    hkcditlqeiiktlnslteqktlcteltvtdifaaskntteketfcraatvlrqfyshhe
    kdtrclgataqqfhrhkqlirflkrldrnlwglaglnscpvkeanqstlenflerlktim
    rekyskcss
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1iarB (B:)
    fkvlqeptcvsdymsistcewkmngptncstelrllyqlvfllseahtcipennggagcv
    chllmddvvsadnytldlwagqqllwkgsfkpsehvkprapgnltvhtnvsdtllltwsn
    pyppdnylynhltyavniwsendpadfriynvtylepslriaastlksgisyrarvrawa
    qaynttwsewspstkwhnsyrepfeqh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1iarB (B:)
    fkvlqeptcvsdymsistcewkmngptncstelrllyqlvfllseahtcipennggagcv
    chllmddvvsadnytldlwagqqllwkgsfkpsehvkprapgnltvhdtllltwsnpypp
    dnylynhltyavniwsendpadfriynvtylepslriaagisyrarvrawaqaynttwse
    wspstkwh