PDB entry 1i7w

View 1i7w on RCSB PDB site
Description: beta-catenin/phosphorylated e-cadherin complex
Class: cell adhesion
Keywords: E-cadherin, cell adhesion, beta-catenin, protein-protein complex, extended interface, armadillo repeat, phosphoserine
Deposited on 2001-03-10, released 2001-05-09
The last revision prior to the SCOP 1.73 freeze date was dated 2003-04-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.206
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: beta-catenin
    Species: MUS MUSCULUS
    Gene: CATNB
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i7wa_
  • Chain 'B':
    Compound: epithelial-cadherin
    Species: MUS MUSCULUS
    Gene: Cdh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09803
      • modified residue (106)
      • modified residue (108)
      • modified residue (114)
    Domains in SCOP 1.73: d1i7wb_
  • Chain 'C':
    Compound: beta-catenin
    Species: MUS MUSCULUS
    Gene: CATNB
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i7wc_
  • Chain 'D':
    Compound: epithelial-cadherin
    Species: MUS MUSCULUS
    Gene: Cdh1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09803
      • modified residue (106)
      • modified residue (108)
      • modified residue (114)
    Domains in SCOP 1.73: d1i7wd_
  • Heterogens: ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i7wA (A:)
havvnlinyqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspq
mvsaivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlf
yaittlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskl
iilasggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdp
sqrlvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyk
nkmmvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpv
vvkllhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsm
ggtqqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieniqrv
aagvlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdyk

    Sequence, based on observed residues (ATOM records): (download) 
    >1i7wA (A:)
atraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtmqntndv
etarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnlllhqeg
akmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpqalvnim
rtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqnclwtlrnl
sdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvggiealv
rtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhppshwplik
atvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrvrmeeivegctgalhilar
dvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieaegataplte
llhsrnegvatyaaavlfrm

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i7wB (B:)
rrrtvvkepllppdddtrdnvyyydeegggeedqdfdlsqlhrgldarpevtrndvaptl
msvpqyrprpanpdeignfidenlkaadsdptappydsllvfdyegsgseaaslsslnss
esdqdqdydylnewgnrfkkladmygggedd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i7wB (B:)
lkaadsdptappydsllvfdyegsgseaaslssldylnewgnrfkkladmy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1i7wC (C:)
havvnlinyqddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspq
mvsaivrtmqntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlf
yaittlhnlllhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskl
iilasggpqalvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdp
sqrlvqnclwtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyk
nkmmvcqvggiealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpv
vvkllhppshwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtsm
ggtqqqfvegvrmeeivegctgalhilardvhnrivirglntiplfvqllyspieniqrv
aagvlcelaqdkeaaeaieaegatapltellhsrnegvatyaaavlfrmsedkpqdyk

    Sequence, based on observed residues (ATOM records): (download) 
    >1i7wC (C:)
qddaelatraipeltkllndedqvvvnkaavmvhqlskkeasrhaimrspqmvsaivrtm
qntndvetarctagtlhnlshhregllaifksggipalvkmlgspvdsvlfyaittlhnl
llhqegakmavrlagglqkmvallnktnvkflaittdclqilaygnqeskliilasggpq
alvnimrtytyekllwttsrvlkvlsvcssnkpaiveaggmqalglhltdpsqrlvqncl
wtlrnlsdaatkqegmegllgtlvqllgsddinvvtcaagilsnltcnnyknkmmvcqvg
giealvrtvlragdreditepaicalrhltsrhqeaemaqnavrlhyglpvvvkllhpps
hwplikatvglirnlalcpanhaplreqgaiprlvqllvrahqdtqrrtvrmeeivegct
galhilardvhnrivirglntiplfvqllyspieniqrvaagvlcelaqdkeaaeaieae
gatapltellhsrnegvatyaaavlfrms

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1i7wD (D:)
rrrtvvkepllppdddtrdnvyyydeegggeedqdfdlsqlhrgldarpevtrndvaptl
msvpqyrprpanpdeignfidenlkaadsdptappydsllvfdyegsgseaaslsslnss
esdqdqdydylnewgnrfkkladmygggedd

    Sequence, based on observed residues (ATOM records): (download) 
    >1i7wD (D:)
dvapidenlkaadsdptappydsllvfdyegsgseaaslsslydylnewgnrfkkladmy