PDB entry 1i72

View 1i72 on RCSB PDB site
Description: human s-adenosylmethionine decarboxylase with covalently bound pyruvoyl group and covalently bound 5'-deoxy-5'-[n-methyl-n-(2-aminooxyethyl) amino]adenosine
Class: lyase
Keywords: Spermidine biosynthesis, Lyase, Decarboxylase, Pyruvate, S-ADENOSYLMETHIONINE, SANDWICH, ALLOSTERIC ENZYME, PYRUVOYL
Deposited on 2001-03-07, released 2001-08-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2010-09-29, with a file datestamp of 2010-09-24.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.201
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: s-adenosylmethionine decarboxylase alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P17707 (0-End)
      • see remark 999 (0)
    Domains in SCOPe 2.01: d1i72.1
  • Chain 'B':
    Compound: s-adenosylmethionine decarboxylase beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1i72.1
  • Heterogens: MAO, PUT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i72A (A:)
xsmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyph
rnfqeeieflnaifpngagycmgrmnsdcwylytldfpesrvisqpdqtleilmseldpa
vmdqfymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpe
pefsyvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrtvlaspqkiegfkr
ldcqsamfndynfvftsfakkqqqqqs

    Sequence, based on observed residues (ATOM records): (download) 
    >1i72A (A:)
xsmfvskrrfilktcgttlllkalvpllklardysgfdsiqsffysrknfmkpshqgyph
rnfqeeieflnaifpngagycmgrmnsdcwylytldfpesqpdqtleilmseldpavmdq
fymkdgvtakdvtresgirdlipgsvidatmfnpcgysmngmksdgtywtihitpepefs
yvsfetnlsqtsyddlirkvvevfkpgkfvttlfvnqsskcrpqkiegfkrldcqsamfn
dynfvftsfakk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i72B (B:)
meaahffegtekllevwfsrqqpdanqgsgdlrtiprsewdillkdvqcsiisvtktdkq
eayvlse

    Sequence, based on observed residues (ATOM records): (download) 
    >1i72B (B:)
ahffegtekllevwfsrqqpqgsgdlrtiprsewdillkdvqcsiisvtktdkqeayvls
e