PDB entry 1i33

View 1i33 on RCSB PDB site
Description: leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase in complex with inhibitors
Class: oxidoreductase
Keywords: enzyme, dehydrogenase, OXIDOREDUCTASE
Deposited on 2001-02-12, released 2001-10-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.211
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33a1, d1i33a2
  • Chain 'B':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33b1, d1i33b2
  • Chain 'C':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33c1, d1i33c2
  • Chain 'D':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33d1, d1i33d2
  • Chain 'E':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33e1, d1i33e2
  • Chain 'F':
    Compound: glyceraldehyde 3-phosphate dehydrogenase
    Species: Leishmania mexicana [TaxId:5665]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1i33f1, d1i33f2
  • Heterogens: TND

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i33A (A:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33A (A:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i33B (B:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33B (B:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1i33C (C:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33C (C:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1i33D (D:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33D (D:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1i33E (E:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33E (E:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1i33F (F:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaasskm

    Sequence, based on observed residues (ATOM records): (download) 
    >1i33F (F:)
apikvgingfgrigrmvfqaicdqgligteidvvavvdmstnaeyfayqmkhdtvhgrpk
ytveavksspsvetadvlvvnghrikcvkaqrnpadlpwgklgvdyviestglftdklka
eghikggakkvvisapasggaktivmgvnqheyspashhvvsnascttnclapivhvltk
enfgietglmttihsytatqktvdgvslkdwrggraaavniipsttgaakavgmvipstk
gkltgmsfrvptpdvsvvdltfratrdtsiqeidkaikkaaqtymkgilgftdeelvsad
findnrssvydskatlqnnlpgekrffkvvswydnewayshrvvdlvrymaakdaass