PDB entry 1i10

View 1i10 on RCSB PDB site
Description: human muscle l-lactate dehydrogenase m chain, ternary complex with nadh and oxamate
Class: oxidoreductase
Keywords: dehydrogenase, rossman fold
Deposited on 2001-01-30, released 2001-03-28
The last revision prior to the SCOP 1.73 freeze date was dated 2003-09-30, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.2
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10a1, d1i10a2
  • Chain 'B':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10b1, d1i10b2
  • Chain 'C':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10c1, d1i10c2
  • Chain 'D':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10d1, d1i10d2
  • Chain 'E':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10e1, d1i10e2
  • Chain 'F':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10f1, d1i10f2
  • Chain 'G':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10g1, d1i10g2
  • Chain 'H':
    Compound: l-lactate dehydrogenase m chain
    Species: HOMO SAPIENS
    Gene: LDHA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1i10h1, d1i10h2
  • Heterogens: ACT, NAI, OXM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10A (A:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10B (B:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10C (C:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10D (D:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10E (E:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10F (F:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1i10G (G:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf

    Sequence, based on observed residues (ATOM records): (download) 
    >1i10G (G:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqnlvqrnvnifkfiipnvvky
spnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvhplschg
wvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayeviklkgy
tswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngisdlvkvt
ltseeearlkksadtlwgiqkelqf

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1i10H (H:)
atlkdqliynllkeeqtpqnkitvvgvgavgmacaisilmkdladelalvdviedklkge
mmdlqhgslflrtpkivsgkdynvtansklviitagarqqegesrlnlvqrnvnifkfii
pnvvkyspnckllivsnpvdiltyvawkisgfpknrvigsgcnldsarfrylmgerlgvh
plschgwvlgehgdssvpvwsgmnvagvslktlhpdlgtdkdkeqwkevhkqvvesayev
iklkgytswaiglsvadlaesimknlrrvhpvstmikglygikddvflsvpcilgqngis
dlvkvtltseeearlkksadtlwgiqkelqf