PDB entry 1i0l

View 1i0l on RCSB PDB site
Description: analysis of an invariant aspartic acid in hprts-asparagine mutant
Class: transferase
Keywords: phosphoribosyltransferase, nucleotide metabolism, purine salvage, ternary complex, catalytic base
Deposited on 2001-01-29, released 2002-05-29
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.21
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27796
      • see remark 999 (22)
      • see remark 999 (65)
      • see remark 999 (85)
      • engineered (114)
    Domains in SCOPe 2.05: d1i0la_
  • Chain 'B':
    Compound: hypoxanthine-guanine phosphoribosyltransferase
    Species: Trypanosoma cruzi [TaxId:5693]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q27796
      • see remark 999 (22)
      • see remark 999 (65)
      • see remark 999 (85)
      • engineered (114)
    Domains in SCOPe 2.05: d1i0lb_
  • Heterogens: MG, 7HP, PRP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1i0lA (A:)
mpreyefaekilfteeeirtrikevakriaddykgkglrpyvnplvlisvlkgsfmftad
lcralcdfnvpvrmeficvssygegltssgqvrmlldtrhsieghhvlivedivntaltl
nylyhmyftrrpaslktvvlldkregrrvpfsadyvvanipnafvigygldyddtyrelr
divvlrpevyaereaargkkqraigsadtdrdakrefhsky

    Sequence, based on observed residues (ATOM records): (download) 
    >1i0lA (A:)
yefaekilfteeeirtrikevakriaddykgkglrpyvnplvlisvlkgsfmftadlcra
lcdfnvpvrmeficvssygegltssgqvrmlldtrhsieghhvlivedivntaltlnyly
hmyftrrpaslktvvlldkregrrvpfsadyvvanipnafvigygldyddtyrelrdivv
lrpevyaereaa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1i0lB (B:)
mpreyefaekilfteeeirtrikevakriaddykgkglrpyvnplvlisvlkgsfmftad
lcralcdfnvpvrmeficvssygegltssgqvrmlldtrhsieghhvlivedivntaltl
nylyhmyftrrpaslktvvlldkregrrvpfsadyvvanipnafvigygldyddtyrelr
divvlrpevyaereaargkkqraigsadtdrdakrefhsky

    Sequence, based on observed residues (ATOM records): (download) 
    >1i0lB (B:)
yefaekilfteeeirtrikevakriaddykgkglrpyvnplvlisvlkgsfmftadlcra
lcdfnvpvrmeficvssygegltssgqvrmlldtrhsieghhvlivedivntaltlnyly
hmyftrrpaslktvvlldkregrrvpfsadyvvanipnafvigygldyddtyrelrdivv
lrpevyaereaarg