PDB entry 1hyr
View 1hyr on RCSB PDB site
Description: crystal structure of human mica in complex with natural killer cell receptor nkg2d
Class: immune system
Keywords: activating nk cell receptor, nkg2d, c-type-lectin like, mic-a, MHC-I, complex, immune system
Deposited on
2001-01-21, released
2001-05-23
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.227
AEROSPACI score: 0.26
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: nkg2-d type II integral membrane protein
Species: Homo sapiens [TaxId:9606]
Gene: NKG2D
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d1hyra_ - Chain 'B':
Compound: nkg2-d type II integral membrane protein
Species: Homo sapiens [TaxId:9606]
Gene: NKG2D
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d1hyrb_ - Chain 'C':
Compound: MHC class I chain-related protein a
Species: Homo sapiens [TaxId:9606]
Gene: MICA-001
Database cross-references and differences (RAF-indexed):
- Uniprot Q9TQ92 (1-274)
- initiating methionine (0)
Domains in SCOPe 2.05: d1hyrc1, d1hyrc2 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1hyrA (A:)
nslfnqevqipltesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvys
kedqdllklvksyhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgy
iencstpntyicmqrtv
Sequence, based on observed residues (ATOM records): (download)
>1hyrA (A:)
esycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvyskedqdllklvksy
hwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgyiencstpntyicm
qrtv
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1hyrB (B:)
nslfnqevqipltesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvys
kedqdllklvksyhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgy
iencstpntyicmqrtv
Sequence, based on observed residues (ATOM records): (download)
>1hyrB (B:)
ipltesycgpcpknwicyknncyqffdesknwyesqascmsqnasllkvyskedqdllkl
vksyhwmglvhiptngswqwedgsilspnlltiiemqkgdcalyassfkgyiencstpnt
yicmqrtv
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1hyrC (C:)
mephslrynltvlswdgsvqsgfltevhldgqpflrcdrqkcrakpqgqwaedvlgnktw
dretrdltgngkdlrmtlahikdqkeglhslqeirvceihednstrssqhfyydgelfls
qnletkewtmpqssraqtlamnvrnflkedamktkthyhamhadclqelrrylksgvvlr
rtvppmvnvtrseasegnitvtcrasgfypwnitlswrqdgvslshdtqqwgdvlpdgng
tyqtwvatricqgeeqrftcymehsgnhsthpvps