PDB entry 1hxa

View 1hxa on RCSB PDB site
Description: crystal structure of teas w273s form 2
Class: lyase
Keywords: ISOPRENOID SYNTHASE, ISOPRENOID CYCLASE, 5-EPI-ARISTOLOCHENE SYNTHASE, ISOPRENOID BIOSYNTHESIS, NATURAL PRODUCTS BIOSYNTHESIS, lyase
Deposited on 2001-01-12, released 2003-06-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.32 Å
R-factor: 0.225
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5-epi-aristolochene synthase
    Species: Nicotiana tabacum [TaxId:4097]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q40577 (Start-547)
      • engineered (272)
      • see remark 999 (531)
    Domains in SCOPe 2.08: d1hxaa1, d1hxaa2
  • Heterogens: MG, FHP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hxaA (A:)
masaavanyeeeivrpvadfspslwgdqflsfsidnqvaekyakeiealkeqtrnmllat
gmkladtlnlidtierlgisyhfekeiddildqiynqnsncndlctsalqfrllrqhgfn
ispeifskfqdengkfkeslasdvlgllnlyeashvrthaddiledalafstihlesaap
hlksplreqvthaleqclhkgvprvetrffissiydkeqsknnvllrfakldfnllqmlh
kqelaqvsrwwkdldfvttlpyardrvvecyfsalgvyfepqysqarvmlvktismisiv
ddtfdaygtvkeleaytdaiqrwdineidrlpdymkisykaildlykdyekelssagrsh
ivchaiermkevvrnynvestwfiegytppvseylsnalatttyyylattsylgmksate
qdfewlsknpkileasviicrviddtatyeveksrgqiatgieccmrdygistkeamakf
qnmaetawkdinegllrptpvstefltpilnlarivevtyihnldgythpeevlkphiin
llvdsiki

    Sequence, based on observed residues (ATOM records): (download) 
    >1hxaA (A:)
spslwgdqflsfsidnqvaekyakeiealkeqtrnmllatgmkladtlnlidtierlgis
yhfekeiddildqiynqnsncndlctsalqfrllrqhgfnispeifskfqdengkfkesl
asdvlgllnlyeashvrthaddiledalafstihlesaaphlksplreqvthaleqclhk
gvprvetrffissiydkeqsknnvllrfakldfnllqmlhkqelaqvsrwwkdldfvttl
pyardrvvecyfsalgvyfepqysqarvmlvktismisivddtfdaygtvkeleaytdai
qrwdineidrlpdymkisykaildlykdyekelssagrshivchaiermkevvrnynves
twfiegytppvseylsnalatttyyylattsylgmksateqdfewlsknpkileasviic
rviddtatyeveksrgqiatgieccmrdygistkeamakfqnmaetawkdinegllrptp
vstefltpilnlarivevtyihnldgythpeevlkphiinllvdsiki