PDB entry 1hwk

View 1hwk on RCSB PDB site
Description: complex of the catalytic portion of human hmg-coa reductase with atorvastatin
Deposited on 2001-01-09, released 2001-05-11
The last revision prior to the SCOP 1.57 freeze date was dated 2001-05-11, with a file datestamp of 2001-05-11.
Experiment type: XRAY
Resolution: 2.22 Å
R-factor: 0.212
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hwkA (A:)
prpneeclqilgnaekgakflsdaeiiqlvnakhipaykletliethergvsirrqllsk
klsepsslqylpyrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegc
lvastnrgcraiglgggassrvladgmtrgpvvrlpracdsaevkawletsegfavikea
fdstsrfarlqklhtsiagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqil
avsgnyctdkkpaainwiegrgksvvceavipakvvrevlkttteamievninknlvgsa
magsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsie
igtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaagh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwkA (A:)
prpneecllsdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylp
yrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcrai
glgggassrvladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqk
lhtsiagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkp
aainwiegrgksvvceavipakvvrevlkttteamievninknlvgsamagsiggynaha
anivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllp
qqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaagh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hwkB (B:)
sdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylpyrdynyslv
mgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggassr
vladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrn
lyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegr
gksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaanivtaiyi
acgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqmlg
vqgackdnpgenarqlarivcgtvmagelslmaalaag

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwkB (B:)
sdaeiiqlvnaykletliethergvsirrqllskklsepsslqylpyrdynyslvmgacc
envigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggassrvladg
mtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrnlyirf
qsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegrgksvv
ceavipakvvrevlkttteamievninknlvgsamagsiggynahaanivtaiyiacgqd
aaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqmlgvqgac
kdnpgenarqlarivcgtvmagelslmaalaag

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hwkC (C:)
lsdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylpyrdynysl
vmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggass
rvladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagr
nlyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwieg
rgksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaanivtaiy
iacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqml
gvqgackdnpgenarqlarivcgtvmagelslmaalaag

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hwkD (D:)
sdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslqylpyrdynyslv
mgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgggassr
vladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrn
lyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegr
gksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaanivtaiyi
acgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqmlg
vqgackdnpgenarqlarivcgtvmagelslmaalaag

    Sequence, based on observed residues (ATOM records): (download) 
    >1hwkD (D:)
sdaeiiqletliethergvsirrqllskklsepsslqylpyrdynyslvmgaccenvigy
mpipvgvagplcldekefqvpmattegclvastnrgcraiglgggassrvladgmtrgpv
vrlpracdsaevkawletsegfavikeafdstsrfarlqklhtsiagrnlyirfqsrsgd
amgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaainwiegrgksvvceavip
akvvrevlkttteamievninknlvgsamagsiggynahaanivtaiyiacgqdaaqnvg
ssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqaclqmlgvqgackdnpge
narqlarivcgtvmagelslmaalaag