PDB entry 1hwg

View 1hwg on RCSB PDB site
Description: 1:2 complex of human growth hormone with its soluble binding protein
Class: complex (hormone/receptor)
Keywords: cytokine, hormone, receptor, hematopoietic, complex (hormone/receptor)
Deposited on 1996-11-13, released 1997-11-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.199
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: growth hormone
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hwga_
  • Chain 'B':
    Compound: growth hormone binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hwgb1, d1hwgb2
  • Chain 'C':
    Compound: growth hormone binding protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hwgc1, d1hwgc2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1hwgA (A:)
    fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
    psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
    iqtlmgrledgsprtgqifkqtyskfdtnshnddallknygllycfrkdmdkvetflriv
    qcrsvegscgf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hwgA (A:)
    fptiplsrlfdnamlrahrlhqlafdtyqefeeayipkeqkysflqnpqtslcfsesipt
    psnreetqqksnlellrisllliqswlepvqflrsvfanslvygasdsnvydllkdleeg
    iqtlmgrledgsprtgqifkqtyskfddallknygllycfrkdmdkvetflrivqcrsve
    gscg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1hwgB (B:)
    fsgseataailsrapwslqsvnpglktnsskepkftkcrsperetfschwtdevhhgtkn
    lgpiqlfytrrntqewtqewkecpdyvsagenscyfnssftsiwipycikltsnggtvde
    kcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiqkgwmvleyelqyke
    vnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefsevlyvtlpqms
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hwgB (B:)
    epkftkcrsperetfschwtdepiqlfytrrntqewtqewkecpdyvsagenscyfnssf
    tsiwipycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweap
    rnadiqkgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsg
    nygefsevlyvtlp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1hwgC (C:)
    fsgseataailsrapwslqsvnpglktnsskepkftkcrsperetfschwtdevhhgtkn
    lgpiqlfytrrntqewtqewkecpdyvsagenscyfnssftsiwipycikltsnggtvde
    kcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiqkgwmvleyelqyke
    vnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefsevlyvtlpqms
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hwgC (C:)
    epkftkcrsperetfschwtdpiqlfytrrnqewkecpdyvsagenscyfnssftsiwip
    ycikltsnggtvdekcfsvdeivqpdppialnwtllnvsltgihadiqvrweaprnadiq
    kgwmvleyelqykevnetkwkmmdpilttsvpvyslkvdkeyevrvrskqrnsgnygefs
    evlyvtlpqms