PDB entry 1hw8

View 1hw8 on RCSB PDB site
Description: complex of the catalytic portion of human hmg-coa reductase with compactin (also known as mevastatin)
Deposited on 2001-01-09, released 2001-05-11
The last revision prior to the SCOP 1.63 freeze date was dated 2001-05-11, with a file datestamp of 2001-05-11.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.191
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hw8A (A:)
eprpneeclqilgnaekgakflsdaeiiqlvnakhipaykletliethergvsirrqlls
kklsepsslqylpyrdynyslvmgaccenvigympipvgvagplcldekefqvpmatteg
clvastnrgcraiglgggassrvladgmtrgpvvrlpracdsaevkawletsegfavike
afdstsrfarlqklhtsiagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqi
lavsgnyctdkkpaainwiegrgksvvceavipakvvrevlkttteamievninknlvgs
amagsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsi
eigtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaag
h

    Sequence, based on observed residues (ATOM records): (download) 
    >1hw8A (A:)
eprpneeclsdaeiiqlvnpaykletliethergvsirrqllskklsepsslqylpyrdy
nyslvmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgcraiglgg
gassrvladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfarlqklhts
iagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctdkkpaain
wiegrgksvvceavipakvvrevlkttteamievninknlvgsamagsiggynahaaniv
taiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtnllpqqac
lqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaagh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hw8B (B:)
rpneeclqilgnaekgakflsdaeiiqlvnakhipaykletliethergvsirrqllskk
lsepsslqylpyrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegcl
vastnrgcraiglgggassrvladgmtrgpvvrlpracdsaevkawletsegfavikeaf
dstsrfarlqklhtsiagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqila
vsgnyctdkkpaainwiegrgksvvceavipakvvrevlkttteamievninknlvgsam
agsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsiei
gtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaag

    Sequence, based on observed residues (ATOM records): (download) 
    >1hw8B (B:)
rpneeclqikflsdaeiiqlvnakhipaykletliethergvsirrqllskklsepsslq
ylpyrdynyslvmgaccenvigympipvgvagplcldekefqvpmattegclvastnrgc
raiglgggassrvladgmtrgpvvrlpracdsaevkawletsegfavikeafdstsrfar
lqklhtsiagrnlyirfqsrsgdamgmnmiskgtekalsklheyfpemqilavsgnyctd
kkpaainwiegrgksvvceavipakvvrevlkttteamievninknlvgsamagsiggyn
ahaanivtaiyiacgqdaaqnvgssncitlmeasgptnedlyisctmpsieigtvgggtn
llpqqaclqmlgvqgackdnpgenarqlarivcgtvmagelslmaalaag

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hw8C (C:)
hergvsirrqllskklsepsslqylpyrdynyslvmgaccenvigympipvgvagplcld
ekefqvpmattegclvastnrgcraiglgggassrvladgmtrgpvvrlpracdsaevka
wletsegfavikeafdstsrfarlqklhtsiagrnlyirfqsrsgdamgmnmiskgteka
lsklheyfpemqilavsgnyctdkkpaainwiegrgksvvceavipakvvrevlktttea
mievninknlvgsamagsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgpt
nedlyisctmpsieigtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvm
agelslmaalaag

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1hw8D (D:)
hergvsirrqllskklsepsslqylpyrdynyslvmgaccenvigympipvgvagplcld
ekefqvpmattegclvastnrgcraiglgggassrvladgmtrgpvvrlpracdsaevka
wletsegfavikeafdstsrfarlqklhtsiagrnlyirfqsrsgdamgmnmiskgteka
lsklheyfpemqilavsgnyctdkkpaainwiegrgksvvceavipakvvrevlktttea
mievninknlvgsamagsiggynahaanivtaiyiacgqdaaqnvgssncitlmeasgpt
nedlyisctmpsieigtvgggtnllpqqaclqmlgvqgackdnpgenarqlarivcgtvm
agelslmaalaa