PDB entry 1hvr
View 1hvr on RCSB PDB site
Description: rational design of potent, bioavailable, nonpeptide cyclic ureas as hiv protease inhibitors
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE, ACID PROTEINASE, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on
1994-02-14, released
1995-01-26
The last revision prior to the SCOPe 2.03 freeze date was dated
2012-02-29, with a file datestamp of
2012-02-24.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.193
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1hvra_ - Chain 'B':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1hvrb_ - Heterogens: XK2
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1hvrA (A:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigatlnf
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1hvrB (B:)
pqvtlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigatlnf