PDB entry 1htl

View 1htl on RCSB PDB site
Description: mutation of a buried residue causes lack of activity but no conformational change: crystal structure of e. coli heat-labile enterotoxin mutant val 97--> lys
Class: enterotoxin
Keywords: enterotoxin
Deposited on 1995-02-15, released 1995-04-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.205
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: heat-labile enterotoxin, subunit a
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P06717
      • conflict (96)
    Domains in SCOPe 2.06: d1htl.1
  • Chain 'C':
    Compound: heat-labile enterotoxin, subunit a
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htl.1
  • Chain 'D':
    Compound: heat-labile enterotoxin, subunit b
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htld_
  • Chain 'E':
    Compound: heat-labile enterotoxin, subunit b
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htle_
  • Chain 'F':
    Compound: heat-labile enterotoxin, subunit b
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htlf_
  • Chain 'G':
    Compound: heat-labile enterotoxin, subunit b
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htlg_
  • Chain 'H':
    Compound: heat-labile enterotoxin, subunit b
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1htlh_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1htlA (A:)
ngdrlyradsrppdeikrsgglmprghneyfdrgtqmninlydhargtqtgfvryddgyv
stslslrsahlagqsilsgystyyiyviatapnmfnkndvlgvysphpyeqevsalggip
ysqiygwyrvnfgviderlhrnreyrdryyrnlniapaedgyrlagfppdhqawreepwi
hhapqgcgnss

    Sequence, based on observed residues (ATOM records): (download) 
    >1htlA (A:)
rlyradsrppdeikrsgglmprghneyfdrgtqmninlydhargtqtgfvryddgyvsts
lslrsahlagqsilsgystyyiyviatapnmfnkndvlgvysphpyeqevsalggipysq
iygwyrvnfgviderlhrnreyrdryyrnlniapaedgyrlagfppdhqawreepwihha
pqgcg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1htlC (C:)
rtitgdtcneetqnlstiylreyqskvkrqifsdyqsevdiynrirdel

    Sequence, based on observed residues (ATOM records): (download) 
    >1htlC (C:)
gdtcneetqnlstiylreyqskvkrqifsdyqsevdiynri

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1htlD (D:)
apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1htlE (E:)
apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1htlF (F:)
apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1htlG (G:)
apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1htlH (H:)
apqtitelcseyrntqiytindkilsytesmagkremviitfksgetfqvevpgsqhids
qkkaiermkdtlrityltetkidklcvwnnktpnsiaaismkn