PDB entry 1hsh
View 1hsh on RCSB PDB site
Description: crystal structure at 1.9 angstroms resolution of human immunodeficiency virus (hiv) II protease complexed with l-735,524, an orally bioavailable inhibitor of the hiv proteases
Class: hydrolase (acid proteinase)
Keywords: hydrolase (acid proteinase)
Deposited on
1995-03-31, released
1996-04-03
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.194
AEROSPACI score: 0.44
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Gene: HIV-1 PROTEASE FROM THE ROD ISOLATE
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1hsha_ - Chain 'B':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Gene: HIV-1 PROTEASE FROM THE ROD ISOLATE
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1hshb_ - Chain 'C':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Gene: HIV-1 PROTEASE FROM THE ROD ISOLATE
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1hshc_ - Chain 'D':
Compound: hiv-1 protease
Species: Human immunodeficiency virus 1 [TaxId:11676]
Gene: HIV-1 PROTEASE FROM THE ROD ISOLATE
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1hshd_ - Heterogens: MK1, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1hshA (A:)
pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
nveievlnkkvratimtgdtpinifgrniltalgmslnl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1hshB (B:)
pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
nveievlnkkvratimtgdtpinifgrniltalgmslnl
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1hshC (C:)
pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
nveievlnkkvratimtgdtpinifgrniltalgmslnl
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1hshD (D:)
pqfslwkrpvvtayiegqpvevlldtgaddsivagielgnnyspkivggiggfintkeyk
nveievlnkkvratimtgdtpinifgrniltalgmslnl