PDB entry 1hsg

View 1hsg on RCSB PDB site
Description: crystal structure at 1.9 angstroms resolution of human immunodeficiency virus (hiv) II protease complexed with l-735,524, an orally bioavailable inhibitor of the hiv proteases
Class: hydrolase (acid proteinase)
Keywords: hydrolase (acid proteinase)
Deposited on 1995-03-31, released 1996-04-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.166
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: HIV-1 PROTEASE FROM THE NY5 ISOLATE
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOPe 2.03: d1hsga_
• Chain 'B':
  Compound: hiv-1 protease
  Species: Human immunodeficiency virus 1 [TaxId:11676]
  Gene: HIV-1 PROTEASE FROM THE NY5 ISOLATE
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03367 (0-98)
  Domains in SCOPe 2.03: d1hsgb_
• Heterogens: MK1, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hsgA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1hsgB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf