PDB entry 1hqr

View 1hqr on RCSB PDB site
Description: crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II
Class: immune system
Keywords: Superantigen-MHC class II complex, IMMUNE SYSTEM
Deposited on 2000-12-19, released 2001-01-03
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.224
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla-dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hqra1, d1hqra2
  • Chain 'B':
    Compound: hla-dr beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hqrb1, d1hqrb2
  • Chain 'C':
    Compound: myelin basic protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: streptococcal pyrogenic exotoxin c
    Species: Streptococcus pyogenes [TaxId:1314]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d1hqrd1, d1hqrd2
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1hqrA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    d
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hqrA (A:)
    eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
    iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
    rngkpvtgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1hqrB (B:)
    gdtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaey
    wnsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvn
    gfypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewra
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hqrB (B:)
    dtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaeyw
    nsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypahnllvcsvngfypgsie
    vrwfrnsqeekagvvstgliqngdwtfqtlvmletvprevytcqvehpsvtspltvewra
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1hqrD (D:)
    dskkdisnvksdllyaytitpydykdcrvnfstthtlnidtqkyrgkdyyissemsyeas
    qkfkrddhvdvfglfyilnshtgeyiyggitpaqnnkvnhkllgnlfisgesqqnlnnki
    ilekdivtfqeidfkirkylmdnykiydatspyvsgrieigtkdgkheqidlfdspnegt
    rsdifakykdnriinmknfshfdiylek
    

    Sequence, based on observed residues (ATOM records): (download)
    >1hqrD (D:)
    kkdisnvksdllyaytitpydykdcrvnfstthtlnidtqkyrgkdyyissemsyeasqk
    fkrddhvdvfglfyilnshtgeyiyggitpaqnnkvnhkllgnlfisgesqqnlnnkiil
    ekdivtfqeidfkirkylmdnykiydatspyvsgrieigtkdgkheqidlfdspnegtrs
    difakykdnriinmknfshfdiylek