PDB entry 1hqr

View 1hqr on RCSB PDB site
Description: crystal structure of a superantigen bound to the high-affinity, zinc-dependent site on MHC class II
Class: immune system
Keywords: Superantigen-MHC class II complex, IMMUNE SYSTEM
Deposited on 2000-12-19, released 2001-01-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.224
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla-dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hqra1, d1hqra2
  • Chain 'B':
    Compound: hla-dr beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hqrb1, d1hqrb2
  • Chain 'C':
    Compound: myelin basic protein
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: streptococcal pyrogenic exotoxin c
    Species: Streptococcus pyogenes [TaxId:1314]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hqrd1, d1hqrd2
  • Heterogens: ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hqrA (A:)
ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
d

    Sequence, based on observed residues (ATOM records): (download) 
    >1hqrA (A:)
eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
iavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtwl
rngkpvtgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hqrB (B:)
gdtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaey
wnsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypartqtlqhhnllvcsvn
gfypgsievrwfrnsqeekagvvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
tspltvewra

    Sequence, based on observed residues (ATOM records): (download) 
    >1hqrB (B:)
dtrprflqqdkyechffngtervrflhrdiynqeedlrfdsdvgeyravtelgrpdaeyw
nsqkdfledrraavdtycrhnygvgesftvqrrvepkvtvypahnllvcsvngfypgsie
vrwfrnsqeekagvvstgliqngdwtfqtlvmletvprevytcqvehpsvtspltvewra

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1hqrD (D:)
dskkdisnvksdllyaytitpydykdcrvnfstthtlnidtqkyrgkdyyissemsyeas
qkfkrddhvdvfglfyilnshtgeyiyggitpaqnnkvnhkllgnlfisgesqqnlnnki
ilekdivtfqeidfkirkylmdnykiydatspyvsgrieigtkdgkheqidlfdspnegt
rsdifakykdnriinmknfshfdiylek

    Sequence, based on observed residues (ATOM records): (download) 
    >1hqrD (D:)
kkdisnvksdllyaytitpydykdcrvnfstthtlnidtqkyrgkdyyissemsyeasqk
fkrddhvdvfglfyilnshtgeyiyggitpaqnnkvnhkllgnlfisgesqqnlnnkiil
ekdivtfqeidfkirkylmdnykiydatspyvsgrieigtkdgkheqidlfdspnegtrs
difakykdnriinmknfshfdiylek