PDB entry 1hq5

View 1hq5 on RCSB PDB site
Description: crystal structure of the binuclear manganese metalloenzyme arginase complexed with s-(2-boronoethyl)-l-cysteine, an l-arginine analogue
Class: hydrolase
Keywords: binuclear manganese cluster, boronic acid inhibitor, perfectly twinned crystal, hydrolase
Deposited on 2000-12-14, released 2001-04-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: arginase 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hq5a_
  • Chain 'B':
    Compound: arginase 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hq5b_
  • Heterogens: MN, S2C, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hq5A (A:)
msskpkpieiigapfskgqprggvekgpaalrkaglveklketeynvrdhgdlafvdvpn
dspfqivknprsvgkaneqlaavvaetqkngtisvvlggdhsmaigsisgharvhpdlcv
iwvdahtdintplttssgnlhgqpvafllkelkgkfpdvpgfswvtpcisakdivyiglr
dvdpgehyiiktlgikyfsmtevdklgigkvmeetfsyllgrkkrpihlsfdvdgldpvf
tpatgtpvvgglsyreglyiteeiyktgllsgldimevnptlgktpeevtrtvntavalt
lscfgtkregnhkpetdylkppk

    Sequence, based on observed residues (ATOM records): (download) 
    >1hq5A (A:)
kpieiigapfskgqprggvekgpaalrkaglveklketeynvrdhgdlafvdvpndspfq
ivknprsvgkaneqlaavvaetqkngtisvvlggdhsmaigsisgharvhpdlcviwvda
htdintplttssgnlhgqpvafllkelkgkfpdvpgfswvtpcisakdivyiglrdvdpg
ehyiiktlgikyfsmtevdklgigkvmeetfsyllgrkkrpihlsfdvdgldpvftpatg
tpvvgglsyreglyiteeiyktgllsgldimevnptlgktpeevtrtvntavaltlscfg
tkregnhk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hq5B (B:)
msskpkpieiigapfskgqprggvekgpaalrkaglveklketeynvrdhgdlafvdvpn
dspfqivknprsvgkaneqlaavvaetqkngtisvvlggdhsmaigsisgharvhpdlcv
iwvdahtdintplttssgnlhgqpvafllkelkgkfpdvpgfswvtpcisakdivyiglr
dvdpgehyiiktlgikyfsmtevdklgigkvmeetfsyllgrkkrpihlsfdvdgldpvf
tpatgtpvvgglsyreglyiteeiyktgllsgldimevnptlgktpeevtrtvntavalt
lscfgtkregnhkpetdylkppk

    Sequence, based on observed residues (ATOM records): (download) 
    >1hq5B (B:)
kpieiigapfskgqprggvekgpaalrkaglveklketeynvrdhgdlafvdvpndspfq
ivknprsvgkaneqlaavvaetqkngtisvvlggdhsmaigsisgharvhpdlcviwvda
htdintplttssgnlhgqpvafllkelkgkfpdvpgfswvtpcisakdivyiglrdvdpg
ehyiiktlgikyfsmtevdklgigkvmeetfsyllgrkkrpihlsfdvdgldpvftpatg
tpvvgglsyreglyiteeiyktgllsgldimevnptlgktpeevtrtvntavaltlscfg
tkregnhk